Interactor 1: TNR16 (P07174)
Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (Low-affinity nerve growth factor receptor p75NGFR) (Low-affinity nerve growth factor receptor p75NGR) (p75 ICD) (CD antigen CD271)
Gene: Ngfr
Interactor 2: A4 (P08592)
Amyloid-beta precursor protein (ABPP) (APP) (Alzheimer disease amyloid A4 protein homolog) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta (A4) precursor protein) (Amyloid-beta A4 protein) (Amyloidogenic glycoprotein) (AG) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Gamma-CTF(50)); C31]
Gene: App
Species: Rattus norvegicus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.60 | 1.00 | 0.776 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | APP_E2~TNFR_c6 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0007417 - central nervous system development GO:0009986 - cell surface and 7 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
