HitPredict

Interactor 1: PYR1 (P07259)
Multifunctional protein URA2 (Pyrimidine-specific carbamoyl phosphate synthase-aspartate carbamoyl transferase) (CPSase-ATCase) [Includes: Glutamine-dependent carbamoyl phosphate synthase (EC 6.3.5.5) (Carbamoyl phosphate synthase P) (CPS-P) (CPSase P) (CPSase-ura) (Pyrimidine-specific carbamoyl phosphate synthase); Glutamine amidotransferase (GATase) (GLNase) (EC 3.5.1.2); Ammonium-dependent carbamoyl phosphate synthase (CPS) (CPSase) (EC 6.3.4.16); Aspartate carbamoyltransferase (ATCase) (EC 2.1.3.2) (Aspartate transcarbamylase)]
Gene: URA2

Interactor 2: HFA1 (P32874)
Acetyl-CoA carboxylase, mitochondrial (ACC) (EC 6.4.1.2) [Includes: Biotin carboxylase (EC 6.3.4.14)]
Gene: HFA1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 22940862
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Biotin_carb_C~CPSase_L_D2, Biotin_carb_N~CPSase_L_D2, Biotin_lipoyl~CPSase_L_D2, CPSase_L_D2~CPSase_L_D2, CPSase_L_D2~CPSase_L_D3, CPSase_L_D2~CPSase_sm_chain, CPSase_L_D2~GATase, CPSase_L_D2~MGS
Common GO terms GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0046872 - metal ion binding
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 2214
Sc

1 2273
+ Hs
+ Hs
+ Hs
+ Sc
+ Dm
+ Ec
+ Hs
+ Hs
+ Hs
+ Hs
+ Nv
+ Ec
+ At
+ Sc
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024