HitPredict

Interactor 1: ISG15 (P05161)
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP)
Gene: ISG15

Interactor 2: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	33024031, 16009940
Identification Methods	affinity chromatography technology, unspecified method
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 165 Hs			1 216
+	At
		836665 UBQ3_ARATH (3-157): 6.93e-64: 199: 33.55		RAN1_ARATH (1-216): 7.47e-96: 280: 73.52
+	At
		836676 UBQ3_ARATH (3-157): 6.93e-64: 199: 33.55		RAN2_ARATH (1-215): 8.76e-89: 262: 74.77
+	At
		1167708 UBQ3_ARATH (3-157): 6.93e-64: 199: 33.55		RAN3_ARATH (1-215): 7.37e-83: 247: 74.31
+	Sc
		376256 UBI4P_YEAST (3-157): 1.09e-61: 196: 32.26		YPT1_YEAST (4-177): 6.94e-83: 246: 28.25
+	Hs
		508600 UBC_HUMAN (3-157): 1.06e-61: 203: 32.26		RAB1B_HUMAN (4-195): 2.99e-80: 239: 28.72
+	At
		701385 UBQ3_ARATH (3-157): 6.93e-64: 199: 33.55		RAD2A_ARATH (4-209): 2.2e-81: 242: 26.79
+	Hs
		507787 UBC_HUMAN (3-157): 1.06e-61: 203: 32.26		RB11A_HUMAN (4-208): 4.29e-78: 235: 26.67
+	Hs
		425422 ISG15_HUMAN (1-165): 4.03e-49: 157: 100.00		RB11A_HUMAN (4-208): 4.29e-78: 235: 26.67
+	Hs
		987361 RL40_HUMAN (3-82): 1.78e-34: 119: 27.50		RAB35_HUMAN (1-188): 1.33e-82: 245: 29.47
+	Rn
		1000474 UBC_RAT (2-110): 5.82e-33: 124: 28.44		RAB8B_RAT (1-204): 2.08e-79: 238: 25.12
+	Rn
		108123 UBC_RAT (2-110): 5.82e-33: 124: 28.44		G3V6H0_RAT (4-196): 1.31e-79: 238: 28.57
+	Rn
		981776 UBC_RAT (2-110): 5.82e-33: 124: 28.44		RAN_RAT (1-216): 1.48e-79: 238: 100.00
+	Hs
		507201 UBB_HUMAN (3-157): 1.11e-66: 204: 32.26		RAB30_HUMAN (11-171): 6.79e-30: 111: 35.37
+	Hs
		508028 UBC_HUMAN (3-157): 1.06e-61: 203: 32.26		RAB30_HUMAN (11-171): 6.79e-30: 111: 35.37
+	Hs
		507694 UBC_HUMAN (3-157): 1.06e-61: 203: 32.26		RAB7A_HUMAN (8-166): 7.47e-29: 108: 33.13
+	Hs
		507517 UBC_HUMAN (3-157): 1.06e-61: 203: 32.26		RAB4A_HUMAN (11-169): 1.54e-27: 105: 34.57