HitPredict

Interactor 1: JUN (P05412)
Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)
Gene: JUN

Interactor 2: PPIA (P62937)
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Cyclosporin A-binding protein) (Rotamase A) [Cleaved into: Peptidyl-prolyl cis-trans isomerase A, N-terminally processed]
Gene: PPIA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	38943005, 25609649
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0006915 - apoptotic process
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 331 Hs			1 165
+	Hs
		430560 JUN_HUMAN (1-331): 8.15e-87: 266: 100.00		PAL4A_HUMAN (1-164): 8.4e-99: 283: 85.98
+	Hs
		429311 JUN_HUMAN (1-331): 8.15e-87: 266: 100.00		PPIB_HUMAN (2-165): 9.5e-88: 257: 63.64
+	Hs
		429529 JUN_HUMAN (1-331): 8.15e-87: 266: 100.00		RBP2_HUMAN (3-164): 1.88e-73: 240: 66.67
+	Hs
		603635 JUNB_HUMAN (1-331): 3.95e-63: 205: 43.89		PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00
+	Hs
		583472 ATF2_HUMAN (47-331): 1.64e-38: 144: 17.33		PPIF_HUMAN (3-164): 6.29e-92: 267: 76.54
+	Hs
		583452 ATF2_HUMAN (47-331): 1.64e-38: 144: 17.33		PPIB_HUMAN (2-165): 9.5e-88: 257: 63.64
+	Hs
		606588 CEBPB_HUMAN (233-312): 1.99e-09: 60.1: 20.73		PPIA_HUMAN (1-165): 2.79e-91: 264: 100.00
+	Hs
		606232 CEBPB_HUMAN (233-312): 1.99e-09: 60.1: 20.73		PPIB_HUMAN (2-165): 9.5e-88: 257: 63.64
+	Hs
		606432 CEBPB_HUMAN (233-312): 1.99e-09: 60.1: 20.73		RBP2_HUMAN (3-164): 1.88e-73: 240: 66.67