Interactor 1: VPS15 (P22219)
Serine/threonine-protein kinase VPS15 (EC 2.7.11.1) (Golgi-retention defective mutant protein 8) (Vacuolar protein sorting-associated protein 15)
Gene: VPS15

Interactor 2: VPS34 (P22543)
Phosphatidylinositol 3-kinase VPS34 (PI3-kinase VPS34) (PI3K VPS34) (PtdIns-3-kinase VPS34) (EC 2.7.1.137) (Carboxypeptidase Y-deficient protein 15) (Vacuolar protein sorting-associated protein 34) (Vacuolar protein-targeting protein 29)
Gene: VPS34

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.750

The method score is based on:

Property Details
Experiments 8387919, 23904270, 24165940, 11689570, 27630019, 37968396, 20489023
Identification Methods coimmunoprecipitation, cross-linking study, affinity chromatography technology, two hybrid, x-ray crystallography, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000139 - Golgi membrane
GO:0000329 - fungal-type vacuole membrane
GO:0000425 - pexophagy
GO:0005524 - ATP binding
GO:0006914 - autophagy
and 10 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1454
Sc

1 875
+ At
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024