HitPredict

Interactor 1: CATL1 (P07711)
Procathepsin L (EC 3.4.22.15) (Cathepsin L1) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L; Cathepsin L heavy chain; Cathepsin L light chain]
Gene: CTSL

Interactor 2: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34709727
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005886 - plasma membrane GO:0043231 - intracellular membrane-bounded organelle GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 333 Hs			1 2472
+	Hs
		637249 CATS_HUMAN (1-333): 5.17e-142: 406: 47.77		SPTN1_HUMAN (1-2472): 0: 714: 100.00
+	Hs
		164553 CATL1_HUMAN (1-333): 5.35e-176: 492: 100.00		SPTN2_HUMAN (141-1932): 1.25e-65: 250: 20.41
+	Hs
		429812 CATL1_HUMAN (1-333): 5.35e-176: 492: 100.00		ACTN1_HUMAN (1862-2210): 3.16e-11: 71.2: 22.25
+	Hs
		211465 CATL1_HUMAN (1-333): 5.35e-176: 492: 100.00		ACTN4_HUMAN (1843-2219): 1.15e-09: 66.2: 20.15
+	Hs
		521471 CATS_HUMAN (1-333): 5.17e-142: 406: 47.77		ACTN1_HUMAN (1862-2210): 3.16e-11: 71.2: 22.25
+	Hs
		211501 CATS_HUMAN (1-333): 5.17e-142: 406: 47.77		ACTN4_HUMAN (1843-2219): 1.15e-09: 66.2: 20.15