HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: RAPH1 (Q70E73)
Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1)
Gene: RAPH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 1250
+	Mm
		923936 PROF1_MOUSE (1-140): 5.37e-77: 226: 95.71		PCLO_MOUSE (489-1249): 2.12e-13: 77.6: 10.18
+	Hs
		430285 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		TITIN_HUMAN (586-1241): 1.11e-11: 71.9: 13.92
+	Mm
		1337493 PROF2_MOUSE (1-140): 9.83e-75: 220: 61.43		PCLO_MOUSE (489-1249): 2.12e-13: 77.6: 10.18