HitPredict

Interactor 1: CD3E (P07766)
T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain) (CD antigen CD3e)
Gene: CD3E

Interactor 2: ES8L2 (Q9H6S3)
Epidermal growth factor receptor kinase substrate 8-like protein 2 (EPS8-like protein 2) (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-related protein 2)
Gene: EPS8L2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17617578
Identification Methods	filamentous phage display
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 207 Hs			1 715
+	Hs
		430697 CD3E_HUMAN (1-207): 5.3e-142: 395: 100.00		EPS8_HUMAN (2-715): 0: 745: 39.73
+	Hs
		430713 CD3E_HUMAN (1-207): 5.3e-142: 395: 100.00		ES8L1_HUMAN (19-713): 0: 653: 38.16
+	Hs
		430712 CD3E_HUMAN (1-207): 5.3e-142: 395: 100.00		ES8L3_HUMAN (24-688): 4e-165: 489: 28.11
+	Hs
		411550 CD3E_HUMAN (1-207): 5.3e-142: 395: 100.00		LCK_HUMAN (416-715): 1.35e-60: 213: 12.79
+	Hs
		208975 CD3E_HUMAN (1-207): 5.3e-142: 395: 100.00		NCK2_HUMAN (492-556): 5.48e-20: 94.5: 30.77
+	Hs
		430679 CD3E_HUMAN (1-207): 5.3e-142: 395: 100.00		NCK1_HUMAN (492-556): 3.45e-16: 83: 27.69