Protein: KDIS
Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)

Gene: KDIS, KIDINS220
Organism: Homo sapiens
Interactions: 229
UniProt ID: Q9ULH0

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0005770 - late endosome
GO:0005829 - cytosol
GO:0010976 - positive regulation of neuron projection development
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

641281

FGFR2
Fibroblast growth factor receptor 2

3

20

High-throughput

0.861

High

1461567

VSIG4
V-set and immunoglobulin domain-containing protein 4

3

5

High-throughput

0.861

High

622706

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

4

High-throughput

0.811

High

901672

RAB7A
Ras-related protein Rab-7a

2

8

High-throughput

0.789

High

976655

RB11A
Ras-related protein Rab-11A

2

1

High-throughput

0.789

High

1186242

CEA21
Cell adhesion molecule CEACAM21

3

4

High-throughput

0.770

High

374275

RASN
GTPase NRas

2

14

High-throughput

0.754

High

376086

RASK
GTPase KRas

2

15

High-throughput

0.754

High

891878

GSK3B
Glycogen synthase kinase-3 beta

2

9

High-throughput

0.754

High

978398

RHOB
Rho-related GTP-binding protein RhoB

2

16

High-throughput

0.754

High

1293933

VSIG1
V-set and immunoglobulin domain-containing protein 1

2

3

High-throughput

0.726

High

1434887

CLMP
CXADR-like membrane protein

2

5

High-throughput

0.726

High

1116619

FHL3
Four and a half LIM domains protein 3

2

6

High-throughput

0.700

High

171784

GAK
Cyclin-G-associated kinase

1

4

High-throughput

0.691

High

750022

KINH
Kinesin-1 heavy chain

1

3

High-throughput

0.691

High

1116126

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.691

High

1451417

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

13

High-throughput

0.691

High

821785

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.679

High

710561

EPHA2
Ephrin type-A receptor 2

2

14

High-throughput

0.675

High

946603

EVA1C
Protein eva-1 homolog C

4

0

High-throughput

0.661

High

627586

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

2

0

High-throughput

0.660

High

855952

CRKL
Crk-like protein

1

4

Small-scale

0.647

High

412794

NTRK1
High affinity nerve growth factor receptor

3

19

Small-scale

0.640

High

749821

CADH5
Cadherin-5

2

2

High-throughput

0.628

High

389561

FINC
Fibronectin

1

3

High-throughput

0.618

High

901100

RAB5C
Ras-related protein Rab-5C

1

3

High-throughput

0.618

High

1153459

CD226
CD226 antigen

1

6

High-throughput

0.618

High

126869

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

364015

EGFR
Epidermal growth factor receptor

1

13

High-throughput

0.618

High

440239

LCK
Tyrosine-protein kinase Lck

1

8

High-throughput

0.618

High

463835

LYN
Tyrosine-protein kinase Lyn

1

8

High-throughput

0.618

High

466521

RHOC
Rho-related GTP-binding protein RhoC

1

13

High-throughput

0.618

High

466599

TNR16
Tumor necrosis factor receptor superfamily member 16

1

4

Small-scale

0.618

High

487872

PARP1
Poly [ADP-ribose] polymerase 1

1

10

High-throughput

0.618

High

581370

RAC2
Ras-related C3 botulinum toxin substrate 2

1

12

High-throughput

0.618

High

593534

PGFRA
Platelet-derived growth factor receptor alpha

1

9

High-throughput

0.618

High

710670

EPHA3
Ephrin type-A receptor 3

1

10

High-throughput

0.618

High

891353

GSK3A
Glycogen synthase kinase-3 alpha

1

8

High-throughput

0.618

High

902138

RAB9A
Ras-related protein Rab-9A

1

8

High-throughput

0.618

High

910249

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

953754

RAC3
Ras-related C3 botulinum toxin substrate 3

1

13

High-throughput

0.618

High

955746

CDC42
Cell division control protein 42 homolog

1

15

High-throughput

0.618

High

956539

RAB2A
Ras-related protein Rab-2A

1

4

High-throughput

0.618

High

962626

RHOA
Transforming protein RhoA

1

15

High-throughput

0.618

High

962856

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.618

High

988816

RAC1
Ras-related C3 botulinum toxin substrate 1

1

13

High-throughput

0.618

High

1015901

RHOG
Rho-related GTP-binding protein RhoG

1

12

High-throughput

0.618

High

1141024

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.618

High

1145166

RAB35
Ras-related protein Rab-35

1

4

High-throughput

0.618

High

1156244

ZYX
Zyxin

1

9

High-throughput

0.618

High

1157108

NTRK3
NT-3 growth factor receptor

1

17

High-throughput

0.618

High

1159554

NTRK2
BDNF/NT-3 growth factors receptor

1

20

High-throughput

0.618

High

1187600

AR13B
ADP-ribosylation factor-like protein 13B

1

4

High-throughput

0.618

High

1256060

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.618

High

1271049

RHOU
Rho-related GTP-binding protein RhoU

1

18

High-throughput

0.618

High

1366910

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.618

High

1438238

RHOF
Rho-related GTP-binding protein RhoF

1

19

High-throughput

0.618

High

1447913

SAR1A
Small COPII coat GTPase SAR1A

1

7

High-throughput

0.618

High

1454798

ANFY1
Rabankyrin-5

1

14

High-throughput

0.618

High

1461573

SAR1B
Small COPII coat GTPase SAR1B

1

4

High-throughput

0.618

High

761308

RYK
Tyrosine-protein kinase RYK

2

17

High-throughput

0.611

High

1436389

MANS1
MANSC domain-containing protein 1

2

0

High-throughput

0.602

High

1022502

IDD
Integral membrane protein DGCR2/IDD

2

2

High-throughput

0.601

High

1454022

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

2

1

High-throughput

0.601

High

540748

LAMP1
Lysosome-associated membrane glycoprotein 1

2

3

High-throughput

0.584

High

1396861

SNX27
Sorting nexin-27

2

14

Small-scale

0.584

High

300527

KRT34
Keratin, type I cuticular Ha4

2

0

High-throughput

0.580

High

720361

UFO
Tyrosine-protein kinase receptor UFO

1

18

High-throughput

0.578

High

388468

B3AT
Band 3 anion transport protein

1

2

High-throughput

0.575

High

935277

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.575

High

1439088

MAGE1
Melanoma-associated antigen E1

2

5

High-throughput

0.574

High

397197

ESR1
Estrogen receptor

2

6

High-throughput

0.571

High

373467

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.561

High

331409

KI20A
Kinesin-like protein KIF20A

1

7

High-throughput

0.553

High

341167

DIRA3
GTP-binding protein Di-Ras3

1

6

High-throughput

0.553

High

601494

RHOQ
Rho-related GTP-binding protein RhoQ

1

15

High-throughput

0.553

High

631017

RAB4A
Ras-related protein Rab-4A

1

4

High-throughput

0.553

High

641701

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

13

High-throughput

0.553

High

648729

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.553

High

845855

MUC18
Cell surface glycoprotein MUC18

1

5

High-throughput

0.553

High

931913

EPHA5
Ephrin type-A receptor 5

1

14

High-throughput

0.553

High

1151927

RHOH
Rho-related GTP-binding protein RhoH

1

15

High-throughput

0.553

High

1396654

RHOV
Rho-related GTP-binding protein RhoV

1

16

High-throughput

0.553

High

1433575

RHOJ
Rho-related GTP-binding protein RhoJ

1

15

High-throughput

0.553

High

64962

ARRD5
Arrestin domain-containing protein 5

1

2

High-throughput

0.536

High

182829

GP182
G-protein coupled receptor 182

1

4

High-throughput

0.536

High

483255

CLCA
Clathrin light chain A

1

1

High-throughput

0.536

High

611413

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

5

High-throughput

0.536

High

862733

UTRN
Utrophin

1

19

High-throughput

0.536

High

1010122

DLK1
Protein delta homolog 1

1

9

High-throughput

0.536

High

1383511

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

1

High-throughput

0.536

High

1403988

SCN2A
Sodium channel protein type 2 subunit alpha

1

7

High-throughput

0.536

High

1407315

CML1
Chemerin-like receptor 1

1

3

High-throughput

0.536

High

255281

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.514

High

619951

VCAM1
Vascular cell adhesion protein 1

1

6

High-throughput

0.514

High

1458326

RHCG
Ammonium transporter Rh type C

1

1

High-throughput

0.514

High

71261

HIDE1
Protein HIDE1

1

0

High-throughput

0.513

High

292774

RENR
Renin receptor

1

0

High-throughput

0.513

High

488889

FURIN
Furin

1

0

High-throughput

0.513

High

1026278

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.513

High

1432449

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

1452889

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.513

High

1453840

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.513

High

1461571

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

1461572

BACE2
Beta-secretase 2

1

0

High-throughput

0.513

High

1406713

SEPT5
Septin-5

1

1

Small-scale

0.512

High

1461570

PHOCN
MOB-like protein phocein

1

5

High-throughput

0.494

High

324061

CSTN1
Calsyntenin-1

1

4

High-throughput

0.489

High

640539

TA2R
Thromboxane A2 receptor

1

2

High-throughput

0.489

High

771265

APJ
Apelin receptor

1

2

High-throughput

0.489

High

914371

EFNA4
Ephrin-A4

1

1

High-throughput

0.489

High

1248406

I27RA
Interleukin-27 receptor subunit alpha

1

8

High-throughput

0.489

High

1249520

VSTM1
V-set and transmembrane domain-containing protein 1

1

3

High-throughput

0.489

High

1454679

MYEF2
Myelin expression factor 2

1

6

High-throughput

0.489

High

180102

BET1
BET1 homolog

1

2

High-throughput

0.479

High

189920

STX7
Syntaxin-7

1

4

High-throughput

0.479

High

226257

STX6
Syntaxin-6

1

2

High-throughput

0.479

High

247460

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

3

High-throughput

0.479

High

291585

NU155
Nuclear pore complex protein Nup155

1

1

High-throughput

0.479

High

299426

FLOT1
Flotillin-1

1

2

High-throughput

0.479

High

327497

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.479

High

346486

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

5

High-throughput

0.479

High

459796

PROF1
Profilin-1

1

3

High-throughput

0.479

High

556412

CADH1
Cadherin-1

1

2

High-throughput

0.479

High

562483

LAMP2
Lysosome-associated membrane glycoprotein 2

1

3

High-throughput

0.479

High

583016

EZRI
Ezrin

1

12

High-throughput

0.479

High

613484

VINC
Vinculin

1

5

High-throughput

0.479

High

643132

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

7

High-throughput

0.479

High

684042

PTN3
Tyrosine-protein phosphatase non-receptor type 3

1

10

High-throughput

0.479

High

715841

MARCS
Myristoylated alanine-rich C-kinase substrate

1

6

High-throughput

0.479

High

726813

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

1

High-throughput

0.479

High

764467

CTNA1
Catenin alpha-1

1

4

High-throughput

0.479

High

872878

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.479

High

895150

EMD
Emerin

1

1

High-throughput

0.479

High

905280

MECP2
Methyl-CpG-binding protein 2

1

3

High-throughput

0.479

High

936480

AFAD
Afadin

1

16

High-throughput

0.479

High

989165

AP2B1
AP-2 complex subunit beta

1

4

High-throughput

0.479

High

1041365

CAV1
Caveolin-1

1

2

High-throughput

0.479

High

1087336

STX4
Syntaxin-4

1

7

High-throughput

0.479

High

1159900

OCLN
Occludin

1

2

High-throughput

0.479

High

1178458

CL16A
Protein CLEC16A

1

2

High-throughput

0.479

High

1252287

SYNE3
Nesprin-3

1

20

High-throughput

0.479

High

1291006

TAXB1
Tax1-binding protein 1

1

9

High-throughput

0.479

High

1353304

PARD3
Partitioning defective 3 homolog

1

9

High-throughput

0.479

High

1395989

DNJC1
DnaJ homolog subfamily C member 1

1

7

High-throughput

0.479

High

1400350

FMNL2
Formin-like protein 2

1

2

High-throughput

0.479

High

1432999

DNJC5
DnaJ homolog subfamily C member 5

1

4

High-throughput

0.479

High

1435440

EGLN3
Prolyl hydroxylase EGLN3

1

6

High-throughput

0.479

High

1447423

ANLN
Anillin

1

1

High-throughput

0.479

High

1453782

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

9

High-throughput

0.479

High

1461563

ALK
ALK tyrosine kinase receptor

1

19

High-throughput

0.479

High

125661

LEG9
Galectin-9

1

0

High-throughput

0.458

High

181027

LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4

1

0

High-throughput

0.458

High

1197749

MIDN
Midnolin

1

0

High-throughput

0.458

High

1276368

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.458

High

1326948

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.458

High

1330439

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

1432381

PININ
Pinin

1

0

High-throughput

0.458

High

1433119

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

1436361

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1240722

CDC73
Parafibromin

1

1

High-throughput

0.457

High

1448551

DISC1
Disrupted in schizophrenia 1 protein

1

5

High-throughput

0.457

High

423439

A4
Amyloid-beta precursor protein

1

3

Small-scale

0.445

High

957034

CXCR4
C-X-C chemokine receptor type 4

1

2

High-throughput

0.445

High

1119358

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

7

High-throughput

0.445

High

1120654

DAG1
Dystroglycan 1

1

5

Small-scale

0.445

High

1131646

MFS10
Major facilitator superfamily domain-containing protein 10

1

3

High-throughput

0.445

High

1251204

ZNT10
Calcium/manganese antiporter SLC30A10

1

5

High-throughput

0.445

High

1288943

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

2

High-throughput

0.445

High

1346829

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

5

High-throughput

0.445

High

1348088

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

1

High-throughput

0.445

High

1400179

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

4

High-throughput

0.445

High

1461564

FLVC2
Choline/ethanolamine transporter FLVCR2

1

1

High-throughput

0.445

High

1461568

ITM2B
Integral membrane protein 2B

1

2

High-throughput

0.445

High

60135

DYTN
Dystrotelin

1

5

High-throughput

0.437

High

140027

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

218949

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.437

High

456162

CSF1R
Macrophage colony-stimulating factor 1 receptor

1

8

High-throughput

0.437

High

604267

CXA1
Gap junction alpha-1 protein

1

2

High-throughput

0.437

High

1229129

RNF43
E3 ubiquitin-protein ligase RNF43

1

1

High-throughput

0.437

High

1235349

STYK1
Tyrosine-protein kinase STYK1

1

14

High-throughput

0.437

High

1249319

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1276952

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

8

High-throughput

0.437

High

1293203

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

1323040

CXD3
Gap junction delta-3 protein

1

2

High-throughput

0.437

High

1335555

CHST4
Carbohydrate sulfotransferase 4

1

1

High-throughput

0.437

High

1382001

CK052
Uncharacterized protein C11orf52

1

2

High-throughput

0.437

High

1394662

TXD15
Thioredoxin domain-containing protein 15

1

1

High-throughput

0.437

High

1434211

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.437

High

1439417

E41LA
Band 4.1-like protein 4A

1

13

High-throughput

0.437

High

1461565

LAMP3
Lysosome-associated membrane glycoprotein 3

1

3

High-throughput

0.437

High

296639

TNF13
Tumor necrosis factor ligand superfamily member 13

1

0

High-throughput

0.426

High

337151

NPT2B
Sodium-dependent phosphate transport protein 2B

1

0

High-throughput

0.426

High

1060589

KLC1
Kinesin light chain 1

1

0

High-throughput

0.426

High

1063086

S20A2
Sodium-dependent phosphate transporter 2

1

0

High-throughput

0.426

High

1242270

NPAL3
NIPA-like protein 3

1

0

High-throughput

0.426

High

1314012

S35F3
Solute carrier family 35 member F3

1

0

High-throughput

0.426

High

1393223

TM169
Transmembrane protein 169

1

0

High-throughput

0.426

High

1408088

SC6A7
Sodium-dependent proline transporter

1

0

High-throughput

0.426

High

1432820

GCP60
Golgi resident protein GCP60

1

0

Small-scale

0.426

High

1439133

ANKH
Mineralization regulator ANKH

1

0

High-throughput

0.426

High

279583

LAT3
Large neutral amino acids transporter small subunit 3

1

1

High-throughput

0.407

High

869528

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

1

High-throughput

0.407

High

914501

EFNB2
Ephrin-B2

1

1

High-throughput

0.407

High

1150502

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

12

High-throughput

0.407

High

1333423

S43A3
Equilibrative nucleobase transporter 1

1

1

High-throughput

0.407

High

1353737

MOT10
Monocarboxylate transporter 10

1

2

High-throughput

0.407

High

1446722

TMM9B
Transmembrane protein 9B

1

1

High-throughput

0.407

High

1461569

S35A3
UDP-N-acetylglucosamine transporter

1

2

High-throughput

0.407

High

1386412

FAF2
FAS-associated factor 2

4

0

High-throughput

0.360

High

1406334

CGRF1
Cell growth regulator with RING finger domain protein 1

3

0

High-throughput

0.347

High

219392

B4GA1
Beta-1,4-glucuronyltransferase 1

3

0

High-throughput

0.345

High

1458408

S53A1
Solute carrier family 53 member 1

3

0

High-throughput

0.345

High

1391391

MRAP2
Melanocortin-2 receptor accessory protein 2

2

0

High-throughput

0.328

High

1460953

DKKL1
Dickkopf-like protein 1

2

0

High-throughput

0.328

High

471317

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.279

Low

1203828

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.279

Low

1399074

TMM74
Transmembrane protein 74

1

0

High-throughput

0.279

Low

1436412

PAAT
ATPase PAAT

1

0

High-throughput

0.279

Low

1015333

ERH
Enhancer of rudimentary homolog

1

0

High-throughput

0.249

Low

1233568

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low

1416701

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.249

Low

835023

S19A1
Reduced folate transporter

1

0

High-throughput

0.232

Low

1102811

UT1
Urea transporter 1

1

0

High-throughput

0.232

Low

1185908

TMM95
Sperm-egg fusion protein TMEM95

1

0

High-throughput

0.232

Low

1336918

VGLU3
Vesicular glutamate transporter 3

1

0

High-throughput

0.232

Low

1382127

FUCT1
GDP-fucose transporter 1

1

0

High-throughput

0.232

Low

1436016

PACC1
Proton-activated chloride channel

1

0

High-throughput

0.232

Low

1461566

CLC11
C-type lectin domain family 11 member A

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025