HitPredict

Interactor 1: SYV (P07806)
Valine--tRNA ligase, mitochondrial (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)
Gene: VAS1

Interactor 2: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31399574, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1104 Sc			1 705
+	Sc
		365594 SYV_YEAST (1-1104): 0: 1188: 100.00		HSP82_YEAST (1-705): 0: 968: 95.63
+	Hs
		431554 SYVC_HUMAN (41-1103): 0: 1081: 47.91		HS90A_HUMAN (4-705): 0: 1013: 60.67
+	Hs
		438559 SYIM_HUMAN (68-1032): 0: 700: 17.51		HS90B_HUMAN (5-705): 0: 1022: 61.15
+	Sc
		450269 SYIC_YEAST (147-1101): 0: 738: 19.63		HSC82_YEAST (1-705): 0: 977: 100.00
+	Hs
		432295 SYIM_HUMAN (68-1032): 0: 700: 17.51		HS90A_HUMAN (4-705): 0: 1013: 60.67
+	Sc
		365612 SYIC_YEAST (147-1101): 0: 738: 19.63		HSP82_YEAST (1-705): 0: 968: 95.63
+	Ca
		804484 Q59RI1_CANAL (135-1103): 0: 735: 18.61		HSP90_CANAL (4-705): 0: 953: 82.36
+	Hs
		438581 SYLC_HUMAN (140-1103): 0: 632: 14.50		HS90B_HUMAN (5-705): 0: 1022: 61.15
+	Hs
		432322 SYLC_HUMAN (140-1103): 0: 632: 14.50		HS90A_HUMAN (4-705): 0: 1013: 60.67