Protein: TBA3
Tubulin alpha-3 chain (EC 3.6.5.-)

Gene: TBA3, TUB3
Organism: Saccharomyces cerevisiae S288C
Interactions: 182
UniProt ID: P09734

Gene Ontology (top 5):
GO:0000070 - mitotic sister chromatid segregation
GO:0000226 - microtubule cytoskeleton organization
GO:0000278 - mitotic cell cycle
GO:0000280 - nuclear division
GO:0005200 - structural constituent of cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

485979

TBA1
Tubulin alpha-1 chain

3

15

High-throughput

0.855

High

386528

TBB
Tubulin beta chain

2

19

Small-scale

0.793

High

486483

STU2
Protein STU2

3

15

Small-scale

0.756

High

486463

TCPZ
T-complex protein 1 subunit zeta

2

20

High-throughput

0.705

High

486433

RPN2
26S proteasome regulatory subunit RPN2

1

1

High-throughput

0.691

High

486390

SSB1
Ribosome-associated molecular chaperone SSB1

3

10

High-throughput

0.650

High

486401

KAR3
Kinesin-like protein KAR3

1

12

Small-scale

0.647

High

486504

TBCB
Tubulin-specific chaperone B

2

17

Small-scale

0.631

High

486403

HSP60
Heat shock protein 60, mitochondrial

1

20

High-throughput

0.618

High

486460

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.618

High

486479

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.618

High

486486

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.618

High

449296

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD/RAD3

2

2

High-throughput

0.588

High

486520

PUF3
mRNA-binding protein PUF3

2

2

High-throughput

0.588

High

366692

HIS2
Histidine biosynthesis trifunctional protein [Includes: Phosphoribosyl-AMP cyclohydrolase

2

0

High-throughput

0.563

High

486529

MAK21
Ribosome biogenesis protein MAK21

2

0

High-throughput

0.563

High

486392

TCPA
T-complex protein 1 subunit alpha

1

20

High-throughput

0.553

High

486461

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.553

High

486462

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.553

High

486470

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.553

High

486387

HSP72
Heat shock protein SSA2

2

10

High-throughput

0.552

High

368305

TRPG
Multifunctional tryptophan biosynthesis protein [Includes: Anthranilate synthase component 2

1

6

High-throughput

0.536

High

416999

VDAC1
Non-selective voltage-gated ion channel 1

1

3

High-throughput

0.536

High

450494

FAS1
Fatty acid synthase subunit beta

1

3

High-throughput

0.536

High

454366

PHO4
Phosphate system positive regulatory protein PHO4

1

1

High-throughput

0.536

High

486388

METK1
S-adenosylmethionine synthase 1

1

1

High-throughput

0.536

High

486425

XPO1
Exportin-1

1

11

High-throughput

0.536

High

486427

EF2
Elongation factor 2

1

8

High-throughput

0.536

High

486440

PRS6B
26S proteasome regulatory subunit 6B homolog

1

2

High-throughput

0.536

High

486447

MAOM
NAD-dependent malic enzyme, mitochondrial

1

1

High-throughput

0.536

High

486456

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.536

High

486476

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.536

High

486477

EMW1
Essential for maintenance of the cell wall protein 1

1

12

High-throughput

0.536

High

486481

SA155
SIT4-associating protein SAP155

1

1

High-throughput

0.536

High

486492

ACS2
Acetyl-coenzyme A synthetase 2

1

2

High-throughput

0.536

High

486497

PRS10
26S proteasome subunit RPT4

1

11

High-throughput

0.536

High

486509

PRS8
26S proteasome regulatory subunit 8 homolog

1

2

High-throughput

0.536

High

486512

CLU
Clustered mitochondria protein 1

1

1

High-throughput

0.536

High

486526

MDN1
Midasin

1

4

High-throughput

0.536

High

486432

EI2BB
Translation initiation factor eIF2B subunit beta

2

3

High-throughput

0.533

High

486507

NUM1
Nuclear migration protein NUM1

1

7

Small-scale

0.515

High

486436

KA122
Importin beta-like protein KAP122

1

0

High-throughput

0.513

High

486515

RPN9
26S proteasome regulatory subunit RPN9

1

0

High-throughput

0.513

High

486385

SSBP1
Single-stranded nucleic acid-binding protein

1

3

High-throughput

0.501

High

440880

CDC7
Cell division control protein 7

1

19

High-throughput

0.500

High

458976

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

3

High-throughput

0.500

High

470085

SPS1
Sporulation-specific protein 1

1

12

High-throughput

0.500

High

486394

KSS1
Mitogen-activated protein kinase KSS1

1

10

High-throughput

0.500

High

486404

PP11
Serine/threonine-protein phosphatase PP1-1

1

8

High-throughput

0.500

High

486407

RFA1
Replication factor A protein 1

1

5

High-throughput

0.500

High

486413

DMC1
Meiotic recombination protein DMC1

1

4

High-throughput

0.500

High

486428

DBF20
Serine/threonine-protein kinase DBF20

1

8

High-throughput

0.500

High

486434

IME2
Meiosis induction protein kinase IME2/SME1

1

10

High-throughput

0.500

High

486443

SIP2
SNF1 protein kinase subunit beta-2

1

3

High-throughput

0.500

High

486452

IMB2
Importin subunit beta-2

1

4

High-throughput

0.500

High

486459

TEM1
Protein TEM1

1

6

High-throughput

0.500

High

486478

SKP2
F-box protein SKP2

1

1

High-throughput

0.500

High

486495

SNT2
E3 ubiquitin-protein ligase SNT2

1

1

High-throughput

0.500

High

486496

BUD32
EKC/KEOPS complex subunit BUD32

1

1

High-throughput

0.500

High

486499

PAP2
Poly(A) RNA polymerase protein 2

1

1

High-throughput

0.500

High

486521

RBX1
RING-box protein HRT1

1

9

High-throughput

0.500

High

486533

LAS17
Proline-rich protein LAS17

1

3

High-throughput

0.500

High

366895

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.489

High

486397

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

4

High-throughput

0.489

High

486402

VATA
V-type proton ATPase catalytic subunit A

1

4

High-throughput

0.489

High

486442

GCN1
eIF-2-alpha kinase activator GCN1

1

9

High-throughput

0.489

High

486506

TMEDA
Endoplasmic reticulum vesicle protein 25

1

2

High-throughput

0.489

High

486468

BIM1
Protein BIM1

1

9

Small-scale

0.481

High

486523

ULS1
ATP-dependent helicase ULS1

1

5

Small-scale

0.481

High

486531

SIZ2
E3 SUMO-protein ligase SIZ2

1

1

Small-scale

0.481

High

486416

DPO4
DNA polymerase IV

1

0

High-throughput

0.479

High

486424

PSO2
DNA cross-link repair protein PSO2/SNM1

1

0

High-throughput

0.479

High

149501

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.479

High

434712

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

435684

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

486393

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.479

High

486398

HSC82
ATP-dependent molecular chaperone HSC82

1

9

High-throughput

0.479

High

486405

RIR1
Ribonucleoside-diphosphate reductase large chain 1

1

2

High-throughput

0.479

High

486406

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

2

High-throughput

0.479

High

486412

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

486417

CDC48
Cell division control protein 48

1

9

High-throughput

0.479

High

486421

URK1
Uridine kinase

1

2

High-throughput

0.479

High

486423

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

486429

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

486437

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

6

High-throughput

0.479

High

486444

DEF1
RNA polymerase II degradation factor 1

1

6

High-throughput

0.479

High

486445

RS27A
Small ribosomal subunit protein eS27A

1

4

High-throughput

0.479

High

486446

CENPA
Histone H3-like centromeric protein CSE4

1

4

High-throughput

0.479

High

486449

GBLP
Small ribosomal subunit protein RACK1

1

18

High-throughput

0.479

High

486455

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

486466

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.479

High

486473

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

486484

MPS3
Spindle pole body assembly component MPS3

1

1

High-throughput

0.479

High

486485

MAD3
Spindle assembly checkpoint component MAD3

1

1

Small-scale

0.479

High

486487

BPL1
Biotin--protein ligase

1

1

High-throughput

0.479

High

486488

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

486490

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

13

High-throughput

0.479

High

486500

HST2
NAD-dependent protein deacetylase HST2

1

5

High-throughput

0.479

High

486508

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

486514

RUVB1
RuvB-like protein 1

1

6

High-throughput

0.479

High

486518

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

486519

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.479

High

486522

SGO1
Shugoshin

1

1

High-throughput

0.479

High

486524

MCA1
Metacaspase-1

1

1

High-throughput

0.479

High

486530

RIO1
Serine/threonine-protein kinase RIO1

1

5

High-throughput

0.479

High

486534

RUVB2
RuvB-like protein 2

1

6

High-throughput

0.479

High

486535

SMC6
Structural maintenance of chromosomes protein 6

1

13

High-throughput

0.479

High

486384

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

486389

AK
Aspartokinase

1

0

High-throughput

0.458

High

486415

SGF29
SAGA complex subunit SGF29

1

0

Small-scale

0.458

High

486426

HS104
Heat shock protein 104

1

0

High-throughput

0.458

High

486457

PIH1
Protein interacting with Hsp90 1

1

0

High-throughput

0.458

High

486465

AIM2
Protein AIM2

1

0

High-throughput

0.458

High

486536

DET1
Broad-range acid phosphatase DET1

1

0

High-throughput

0.458

High

486475

BNI1
Protein BNI1

1

4

High-throughput

0.457

High

486450

ANM1
Protein arginine N-methyltransferase 1

1

8

High-throughput

0.457

High

486391

SIR4
Regulatory protein SIR4

1

1

High-throughput

0.457

High

486396

EI2BA
Translation initiation factor eIF2B subunit alpha

1

3

High-throughput

0.457

High

486409

RAD57
DNA repair protein RAD57

1

4

High-throughput

0.457

High

486411

YCP2
Uncharacterized protein YCR001W

1

1

High-throughput

0.457

High

486430

ARP2
Actin-related protein 2

1

7

High-throughput

0.457

High

486453

ATG12
Ubiquitin-like protein ATG12

1

1

High-throughput

0.457

High

486474

COPB2
Coatomer subunit beta'

1

11

High-throughput

0.457

High

486493

SEH1
Nucleoporin SEH1

1

10

High-throughput

0.457

High

486498

COPA
Coatomer subunit alpha

1

12

High-throughput

0.457

High

486516

KU80
ATP-dependent DNA helicase II subunit 2

1

4

High-throughput

0.457

High

392054

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.445

High

394134

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

453361

PYR1
Multifunctional protein URA2

1

13

High-throughput

0.445

High

486386

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.445

High

486399

HSP26
Heat shock protein 26

1

1

High-throughput

0.445

High

486400

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.445

High

486408

SIS1
Protein SIS1

1

16

High-throughput

0.445

High

486410

SCJ1
DnaJ-related protein SCJ1

1

16

High-throughput

0.445

High

486414

MAS5
Mitochondrial protein import protein MAS5

1

19

High-throughput

0.445

High

486419

SYLC
Leucine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.445

High

486422

SPT5
Transcription elongation factor SPT5

1

5

High-throughput

0.445

High

486431

NUP2
Nucleoporin NUP2

1

2

High-throughput

0.445

High

486435

HSP7F
Heat shock protein homolog SSE1

1

13

High-throughput

0.445

High

486439

PRS6A
26S proteasome regulatory subunit 6A

1

3

High-throughput

0.445

High

486451

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

20

High-throughput

0.445

High

486458

SSZ1
Ribosome-associated complex subunit SSZ1

1

7

High-throughput

0.445

High

486469

SSB2
Ribosome-associated molecular chaperone SSB2

1

10

High-throughput

0.445

High

486491

PFD6
Prefoldin subunit 6

1

7

High-throughput

0.445

High

486501

NOG2
Nucleolar GTP-binding protein 2

1

2

High-throughput

0.445

High

486502

JJJ1
J protein JJJ1

1

20

High-throughput

0.445

High

486503

NOP13
Nucleolar protein 13

1

9

High-throughput

0.445

High

486510

FCP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

8

High-throughput

0.445

High

383432

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

409853

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

433361

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

441620

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.437

High

454784

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

486379

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

486381

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.437

High

486383

RL18B
Large ribosomal subunit protein eL18B

1

1

High-throughput

0.437

High

486418

SPB4
ATP-dependent rRNA helicase SPB4

1

2

High-throughput

0.437

High

486420

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

486438

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

486441

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

486464

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

486482

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

5

High-throughput

0.437

High

486489

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.437

High

486525

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

486532

DBP10
ATP-dependent RNA helicase DBP10

1

1

High-throughput

0.437

High

454055

DHE4
NADP-specific glutamate dehydrogenase 1

1

0

High-throughput

0.426

High

486467

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.426

High

486494

MDS3
Negative regulator of sporulation MDS3

1

0

High-throughput

0.426

High

486528

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.426

High

486448

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

3

High-throughput

0.407

High

486454

GRPE
GrpE protein homolog, mitochondrial

1

1

High-throughput

0.407

High

486471

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

4

High-throughput

0.407

High

486472

ICE2
Protein ICE2

1

1

High-throughput

0.407

High

486505

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

5

High-throughput

0.407

High

486511

SCS7
Ceramide very long chain fatty acid hydroxylase SCS7

1

1

High-throughput

0.407

High

486517

ERV41
ER-derived vesicles protein ERV41

1

1

High-throughput

0.407

High

486480

GCN20
Protein GCN20

1

0

High-throughput

0.279

Low

486513

YD131
F-box protein YDR131C

1

0

High-throughput

0.261

Low

486380

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

486382

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

486527

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

486395

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025