HitPredict

Interactor 1: SRC (P05480)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: TRPC1 (Q61056)
Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (TRP-1) (mTrp1) (Trp-related protein 1)
Gene: TRPC1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	16407161
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 535 Mm			1 793
+	Mm
		431375 SRC_MOUSE (1-535): 0: 648: 100.00		TRPC5_MOUSE (26-793): 3.5e-171: 521: 44.94
+	Mm
		431372 SRC_MOUSE (1-535): 0: 648: 100.00		TRPC4_MOUSE (25-790): 3.14e-164: 502: 46.15
+	Mm
		431352 SRC_MOUSE (1-535): 0: 648: 100.00		TRPC6_MOUSE (39-792): 5.38e-151: 467: 33.02
+	Hs
		557536 SRC_HUMAN (1-535): 0: 640: 98.69		TRPC6_HUMAN (48-789): 4.39e-150: 464: 33.01
+	Mm
		431377 SRC_MOUSE (1-535): 0: 648: 100.00		TRPC2_MOUSE (51-781): 8.99e-130: 417: 30.47
+	Hs
		440793 FYN_HUMAN (1-535): 0: 594: 68.70		TRPC6_HUMAN (48-789): 4.39e-150: 464: 33.01
+	Hs
		557477 SRC_HUMAN (1-535): 0: 640: 98.69		TRPV4_HUMAN (51-785): 3.38e-77: 269: 11.47
+	Hs
		463226 YES_HUMAN (1-535): 0: 608: 73.85		TRPV4_HUMAN (51-785): 3.38e-77: 269: 11.47
+	Hs
		440735 FYN_HUMAN (1-535): 0: 594: 68.70		TRPV4_HUMAN (51-785): 3.38e-77: 269: 11.47
+	Hs
		473474 HCK_HUMAN (1-530): 0: 562: 55.66		TRPV4_HUMAN (51-785): 3.38e-77: 269: 11.47
+	Hs
		440217 LCK_HUMAN (57-533): 0: 550: 56.79		TRPV4_HUMAN (51-785): 3.38e-77: 269: 11.47
+	Hs
		463777 LYN_HUMAN (1-530): 0: 531: 52.92		TRPV4_HUMAN (51-785): 3.38e-77: 269: 11.47