HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: BCR (P11274)
Breakpoint cluster region protein (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-26)
Gene: BCR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	21248063, 20675402, 16723087
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0032991 - protein-containing complex and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 1271
+	Hs
		69196 HS90B_HUMAN (19-732): 0: 1059: 86.13		A9UEZ6_HUMAN (1-599): 3.23e-157: 515: 99.00
+	Hs
		431951 HS90A_HUMAN (1-732): 0: 1087: 100.00		SYDE2_HUMAN (746-1264): 9.37e-78: 282: 23.01
+	Hs
		438536 HS90B_HUMAN (19-732): 0: 1059: 86.13		ECT2_HUMAN (335-923): 3.96e-71: 259: 17.07
+	Hs
		431872 HS90A_HUMAN (1-732): 0: 1087: 100.00		RBP1_HUMAN (1051-1211): 4.99e-20: 98.2: 34.55
+	Hs
		538404 ENPL_HUMAN (14-701): 0: 898: 46.78		ECT2_HUMAN (335-923): 3.96e-71: 259: 17.07
+	Sc
		366338 HSP82_YEAST (16-732): 0: 907: 60.08		BEM2_YEAST (1027-1212): 7.89e-20: 98.6: 35.18
+	Sc
		543789 HSC82_YEAST (16-732): 0: 902: 59.39		BEM2_YEAST (1027-1212): 7.89e-20: 98.6: 35.18