HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: KPYM (P14618)
Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Threonine-protein kinase PKM2) (EC 2.7.11.1) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (Tyrosine-protein kinase PKM2) (EC 2.7.10.2) (p58)
Gene: PKM

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

The method score is based on:

Property	Details
Experiments	31273033, 16263121
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005524 - ATP binding GO:0005576 - extracellular region GO:0005634 - nucleus and 9 others more... GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0023026 - MHC class II protein complex binding GO:0034774 - secretory granule lumen GO:0042803 - protein homodimerization activity GO:0062023 - collagen-containing extracellular matrix GO:0070062 - extracellular exosome GO:1904813 - ficolin-1-rich granule lumen
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	732
Hs

1	531

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024