HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.672

Property	Details
Experiments	31980649, 23629654, 22939624, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001764 - neuron migration GO:0005524 - ATP binding GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 732 Hs			1 894
+	Hs
		431562 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHA3_HUMAN (2-831): 0: 646: 19.34
+	Hs
		431692 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHA4_HUMAN (2-836): 0: 637: 19.40
+	Hs
		431691 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHB1_HUMAN (2-833): 0: 621: 20.70
+	Hs
		431561 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHA2_HUMAN (3-837): 0: 604: 19.66
+	Hs
		431788 HS90A_HUMAN (1-732): 0: 1087: 100.00		MERTK_HUMAN (7-861): 0: 588: 40.53
+	Hs
		431531 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHA1_HUMAN (1-837): 0: 555: 20.58
+	Hs
		437892 HS90B_HUMAN (19-732): 0: 1059: 86.13		EPHA1_HUMAN (1-837): 0: 555: 20.58
+	Hs
		431591 HS90A_HUMAN (1-732): 0: 1087: 100.00		TIE1_HUMAN (16-809): 4.24e-158: 494: 21.82
+	Hs
		431444 HS90A_HUMAN (1-732): 0: 1087: 100.00		MET_HUMAN (536-799): 3.42e-66: 243: 45.90
+	Hs
		437816 HS90B_HUMAN (19-732): 0: 1059: 86.13		MET_HUMAN (536-799): 3.42e-66: 243: 45.90
+	Hs
		431764 HS90A_HUMAN (1-732): 0: 1087: 100.00		RON_HUMAN (518-810): 1.36e-56: 214: 40.47
+	Hs
		431765 HS90A_HUMAN (1-732): 0: 1087: 100.00		FAK1_HUMAN (527-851): 1.72e-56: 213: 36.83
+	Hs
		431536 HS90A_HUMAN (1-732): 0: 1087: 100.00		FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29
+	Hs
		431770 HS90A_HUMAN (1-732): 0: 1087: 100.00		TYRO3_HUMAN (8-328): 1.16e-14: 80.5: 16.42
+	Hs
		169159 HS90A_HUMAN (1-732): 0: 1087: 100.00		MUSK_HUMAN (2-147): 3.72e-14: 79: 11.26
+	Hs
		431472 HS90A_HUMAN (1-732): 0: 1087: 100.00		FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69
+	Hs
		431438 HS90A_HUMAN (1-732): 0: 1087: 100.00		IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07
+	Hs
		169160 HS90B_HUMAN (19-732): 0: 1059: 86.13		MUSK_HUMAN (2-147): 3.72e-14: 79: 11.26
+	Hs
		437838 HS90B_HUMAN (19-732): 0: 1059: 86.13		FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69
+	Hs
		435497 HS90B_HUMAN (19-732): 0: 1059: 86.13		IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07