HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: MATK (P42679)
Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic consensus tyrosine-lacking kinase) (Protein kinase HYL) (Tyrosine-protein kinase CTK)
Gene: MATK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22939624
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 732 Hs			1 507
+	Hs
		411945 HS90A_HUMAN (1-732): 0: 1087: 100.00		FYN_HUMAN (28-493): 0: 527: 32.23
+	Hs
		431433 HS90A_HUMAN (1-732): 0: 1087: 100.00		YES_HUMAN (4-493): 0: 523: 31.94
+	Hs
		431481 HS90A_HUMAN (1-732): 0: 1087: 100.00		SRC_HUMAN (30-493): 0: 523: 34.52
+	Hs
		431451 HS90A_HUMAN (1-732): 0: 1087: 100.00		FGR_HUMAN (4-494): 0: 519: 32.03
+	Hs
		411551 HS90A_HUMAN (1-732): 0: 1087: 100.00		LCK_HUMAN (39-492): 1.32e-180: 518: 34.62
+	Hs
		431445 HS90A_HUMAN (1-732): 0: 1087: 100.00		HCK_HUMAN (26-490): 3.62e-178: 512: 33.47
+	Hs
		431627 HS90A_HUMAN (1-732): 0: 1087: 100.00		FRK_HUMAN (22-494): 1.41e-173: 500: 30.91
+	Hs
		337312 HS90A_HUMAN (1-732): 0: 1087: 100.00		ABL1_HUMAN (26-486): 1.44e-165: 499: 32.70
+	Hs
		431619 HS90A_HUMAN (1-732): 0: 1087: 100.00		CSK_HUMAN (45-485): 8.23e-174: 498: 53.05
+	Hs
		431626 HS90A_HUMAN (1-732): 0: 1087: 100.00		ABL2_HUMAN (13-503): 2.01e-164: 498: 31.37
+	Rn
		948934 HS90A_RAT (1-732): 0: 1085: 97.95		LYN_RAT (14-490): 7.04e-172: 496: 31.53
+	Hs
		431434 HS90A_HUMAN (1-732): 0: 1087: 100.00		LYN_HUMAN (14-490): 4.73e-171: 493: 31.73
+	Hs
		431782 HS90A_HUMAN (1-732): 0: 1087: 100.00		ITK_HUMAN (33-484): 4.01e-169: 493: 33.12
+	Hs
		411556 HS90B_HUMAN (19-732): 0: 1059: 86.13		LCK_HUMAN (39-492): 1.32e-180: 518: 34.62
+	Hs
		431666 HS90A_HUMAN (1-732): 0: 1087: 100.00		BLK_HUMAN (10-492): 2.69e-169: 489: 32.66
+	Hs
		337314 HS90B_HUMAN (19-732): 0: 1059: 86.13		ABL1_HUMAN (26-486): 1.44e-165: 499: 32.70
+	Hs
		432259 HS90A_HUMAN (1-732): 0: 1087: 100.00		SRMS_HUMAN (1-483): 6.75e-160: 464: 34.34
+	Hs
		431927 HS90A_HUMAN (1-732): 0: 1087: 100.00		Q573B4_HUMAN (25-492): 3.64e-154: 451: 30.56
+	Hs
		431507 HS90A_HUMAN (1-732): 0: 1087: 100.00		FER_HUMAN (75-478): 2.04e-80: 268: 38.86
+	Hs
		431838 HS90A_HUMAN (1-732): 0: 1087: 100.00		PTK6_HUMAN (66-479): 8.11e-80: 258: 38.73