Protein: SH3R1
E3 ubiquitin-protein ligase SH3RF1 (EC 2.3.2.27) (Plenty of SH3s) (Protein POSH) (RING finger protein 142) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) (SH3 multiple domains protein 2)

Gene: SH3R1, SH3RF1
Organism: Homo sapiens
Interactions: 95
UniProt ID: Q7Z6J0

Gene Ontology (top 5):
GO:0001764 - neuron migration
GO:0005078 - MAP-kinase scaffold activity
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

682191

AKT2
RAC-beta serine/threonine-protein kinase

3

9

Small-scale

0.878

High

895828

UB2D3
Ubiquitin-conjugating enzyme E2 D3

2

7

Small-scale

0.778

High

896478

UBE2N
Ubiquitin-conjugating enzyme E2 N

2

7

Small-scale

0.778

High

681922

AKT1
RAC-alpha serine/threonine-protein kinase

1

8

Small-scale

0.757

High

1083513

M3K11
Mitogen-activated protein kinase kinase kinase 11

1

9

Small-scale

0.724

High

925396

RAC1
Ras-related C3 botulinum toxin substrate 1

5

20

Small-scale

0.712

High

904783

1433G
14-3-3 protein gamma

3

20

High-throughput

0.667

High

849352

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

7

Small-scale

0.647

High

1191843

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

16

Small-scale

0.647

High

199122

SIAH2
E3 ubiquitin-protein ligase SIAH2

2

13

Small-scale

0.636

High

1062914

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

Small-scale

0.633

High

683498

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.628

High

146683

SOCS7
Suppressor of cytokine signaling 7

1

12

High-throughput

0.621

High

298986

SRBS2
Sorbin and SH3 domain-containing protein 2

1

18

High-throughput

0.621

High

302685

ARHGF
Rho guanine nucleotide exchange factor 15

1

15

High-throughput

0.621

High

537657

NCF1
Neutrophil cytosol factor 1

1

20

High-throughput

0.621

High

840747

DYN2
Dynamin-2

1

20

High-throughput

0.621

High

872179

RD23A
UV excision repair protein RAD23 homolog A

1

16

High-throughput

0.621

High

883359

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

1

19

High-throughput

0.621

High

896328

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

9

High-throughput

0.621

High

957987

FGD1
FYVE, RhoGEF and PH domain-containing protein 1

1

10

High-throughput

0.621

High

1024136

LCP2
Lymphocyte cytosolic protein 2

1

20

High-throughput

0.621

High

1043687

ASPP2
Apoptosis-stimulating of p53 protein 2

1

10

High-throughput

0.621

High

1064304

ACAP1
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

1

12

High-throughput

0.621

High

1126368

SH319
SH3 domain-containing protein 19

1

20

High-throughput

0.621

High

1191861

SH24A
SH2 domain-containing protein 4A

1

20

High-throughput

0.621

High

338633

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.618

High

433859

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.618

High

435682

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.618

High

475981

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

20

Small-scale

0.618

High

608026

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.618

High

1191849

SH3R2
E3 ubiquitin-protein ligase SH3RF2

1

19

Small-scale

0.618

High

1191863

UBQL2
Ubiquilin-2

1

12

High-throughput

0.618

High

823431

PAXI
Paxillin

2

12

High-throughput

0.586

High

1191850

PDC6I
Programmed cell death 6-interacting protein

1

20

Small-scale

0.578

High

940670

3BP2
SH3 domain-binding protein 2

1

16

High-throughput

0.555

High

1191848

IKBD
NF-kappa-B inhibitor delta

1

7

High-throughput

0.555

High

684162

1433S
14-3-3 protein sigma

1

20

High-throughput

0.554

High

909744

1433E
14-3-3 protein epsilon

1

12

High-throughput

0.554

High

982211

1433F
14-3-3 protein eta

1

20

High-throughput

0.554

High

1054991

FAT1
Protocadherin Fat 1

1

1

Small-scale

0.552

High

647055

1433T
14-3-3 protein theta

1

20

High-throughput

0.536

High

927227

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

1191852

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

1191846

M4K3
Mitogen-activated protein kinase kinase kinase kinase 3

1

20

High-throughput

0.494

High

126942

WASL
Actin nucleation-promoting factor WASL

1

20

High-throughput

0.481

High

206690

WIPF1
WAS/WASL-interacting protein family member 1

1

20

High-throughput

0.481

High

869487

ATN1
Atrophin-1

1

17

High-throughput

0.481

High

987433

MTG8
Protein CBFA2T1

1

3

High-throughput

0.481

High

1027613

CBLB
E3 ubiquitin-protein ligase CBL-B

1

20

High-throughput

0.481

High

1044784

RIN1
Ras and Rab interactor 1

1

20

High-throughput

0.481

High

1050691

FHL2
Four and a half LIM domains protein 2

1

11

High-throughput

0.481

High

1081086

CCDC6
Coiled-coil domain-containing protein 6

1

17

High-throughput

0.481

High

1191856

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

1

High-throughput

0.481

High

1191859

RN208
RING finger protein 208

1

3

High-throughput

0.481

High

1191864

EVL
Ena/VASP-like protein

1

20

High-throughput

0.481

High

130967

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

13

High-throughput

0.479

High

201952

WDR62
WD repeat-containing protein 62

1

3

Small-scale

0.479

High

522033

CADH1
Cadherin-1

1

6

High-throughput

0.479

High

974897

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

1026928

PAK2
Serine/threonine-protein kinase PAK 2

1

20

Small-scale

0.479

High

1034759

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

1

20

Small-scale

0.479

High

1041919

CUL3
Cullin-3

1

2

High-throughput

0.479

High

1080699

ZYX
Zyxin

1

18

High-throughput

0.479

High

1148119

RNF43
E3 ubiquitin-protein ligase RNF43

1

20

High-throughput

0.479

High

1191845

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

13

Small-scale

0.479

High

1191851

RFFL
E3 ubiquitin-protein ligase rififylin

1

5

Small-scale

0.479

High

1191855

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.479

High

1191867

NINL
Ninein-like protein

1

5

High-throughput

0.479

High

1191860

SEM6A
Semaphorin-6A

1

4

Small-scale

0.464

High

283278

S22A5
Organic cation/carnitine transporter 2

1

0

High-throughput

0.460

High

1191847

MTURN
Maturin

1

0

High-throughput

0.460

High

1191865

SUFU
Suppressor of fused homolog

1

0

High-throughput

0.460

High

273867

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

1191858

UNK
RING finger protein unkempt homolog

1

0

High-throughput

0.458

High

347188

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.445

High

50825

NTM2F
NUT family member 2F

1

4

High-throughput

0.439

High

60603

VP37C
Vacuolar protein sorting-associated protein 37C

1

20

High-throughput

0.439

High

234079

ONEC3
One cut domain family member 3

1

2

High-throughput

0.439

High

953091

PR20A
Proline-rich protein 20A

1

3

High-throughput

0.439

High

1073686

SF3A2
Splicing factor 3A subunit 2

1

19

High-throughput

0.439

High

1134025

AT7L2
Ataxin-7-like protein 2

1

2

High-throughput

0.439

High

1173612

XIRP1
Xin actin-binding repeat-containing protein 1

1

2

High-throughput

0.439

High

1191844

GGN
Gametogenetin

1

17

High-throughput

0.439

High

1191853

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

High-throughput

0.439

High

1191857

PRAM
PML-RARA-regulated adapter molecule 1

1

19

High-throughput

0.439

High

1191862

SYP2L
Synaptopodin 2-like protein

1

10

High-throughput

0.439

High

1191866

DLGP4
Disks large-associated protein 4

1

12

High-throughput

0.439

High

100902

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

824147

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

7

Small-scale

0.437

High

1159384

FBX42
F-box only protein 42

1

2

High-throughput

0.437

High

816144

KCNJ1
ATP-sensitive inward rectifier potassium channel 1

1

0

Small-scale

0.301

High

1191854

EAF1
ELL-associated factor 1

1

0

High-throughput

0.251

Low

984271

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024