HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28007913
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0042981 - regulation of apoptotic process
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 870
+	Hs
		431504 HS90A_HUMAN (1-732): 0: 1087: 100.00		MUC1_HUMAN (84-764): 2.92e-34: 143: 8.84
+	Hs
		431776 HS90A_HUMAN (1-732): 0: 1087: 100.00		ACK1_HUMAN (9-499): 2.55e-30: 131: 15.35
+	Hs
		438103 HS90B_HUMAN (19-732): 0: 1059: 86.13		ACK1_HUMAN (9-499): 2.55e-30: 131: 15.35
+	Hs
		297955 HS90B_HUMAN (19-732): 0: 1059: 86.13		FCSD2_HUMAN (3-156): 3.32e-24: 110: 24.68
+	Hs
		438364 HS90B_HUMAN (19-732): 0: 1059: 86.13		KMT2C_HUMAN (103-742): 2.42e-12: 73.4: 10.09
+	Hs
		992583 H90B3_HUMAN (19-732): 0: 728: 65.41		ACK1_HUMAN (9-499): 2.55e-30: 131: 15.35