HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: LG3BP (Q08380)
Galectin-3-binding protein (Basement membrane autoantigen p105) (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (MAC2BP) (Mac-2 BP) (Tumor-associated antigen 90K)
Gene: LGALS3BP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	31273033, 22939624, 23443559
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0016020 - membrane GO:0062023 - collagen-containing extracellular matrix GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 585
+	Hs
		438105 HS90B_HUMAN (19-732): 0: 1059: 86.13		LG3BP_HUMAN (1-585): 0: 646: 100.00
+	Hs
		432115 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLHL6_HUMAN (139-506): 2.49e-85: 279: 15.31
+	Hs
		432290 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLHL1_HUMAN (93-506): 8.26e-83: 276: 14.91
+	Hs
		432323 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLH13_HUMAN (104-516): 9.08e-83: 273: 15.86
+	Hs
		431841 HS90A_HUMAN (1-732): 0: 1087: 100.00		KEAP1_HUMAN (110-507): 3.23e-82: 271: 14.74
+	Hs
		432143 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLH29_HUMAN (110-506): 7.03e-76: 260: 15.02
+	Hs
		431957 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLH10_HUMAN (116-509): 3.35e-77: 258: 13.50
+	Hs
		431925 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLH26_HUMAN (128-436): 3.37e-76: 255: 16.29
+	Hs
		438402 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLHL6_HUMAN (139-506): 2.49e-85: 279: 15.31
+	Hs
		438555 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLHL1_HUMAN (93-506): 8.26e-83: 276: 14.91
+	Hs
		438582 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLH13_HUMAN (104-516): 9.08e-83: 273: 15.86
+	Hs
		438163 HS90B_HUMAN (19-732): 0: 1059: 86.13		KEAP1_HUMAN (110-507): 3.23e-82: 271: 14.74
+	Hs
		438426 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLH29_HUMAN (110-506): 7.03e-76: 260: 15.02
+	Hs
		438266 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLH10_HUMAN (116-509): 3.35e-77: 258: 13.50
+	Hs
		438236 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLH26_HUMAN (128-436): 3.37e-76: 255: 16.29
+	Hs
		432394 HS90A_HUMAN (1-732): 0: 1087: 100.00		LOXL2_HUMAN (24-125): 1.86e-18: 91.3: 34.82
+	Hs
		538455 ENPL_HUMAN (14-701): 0: 898: 46.78		LOXL2_HUMAN (24-125): 1.86e-18: 91.3: 34.82