HitPredict

Interactor 1: HNRPC (P07910)
Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1/C2)
Gene: HNRNPC

Interactor 2: HNRPL (P14866)
Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
Gene: HNRNPL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~RRM_5
Common GO terms	GO:0000785 - chromatin GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 306 Hs			1 589
+	Hs
		541190 RALY_HUMAN (2-298): 3.88e-63: 203: 40.19		HNRPL_HUMAN (1-589): 5.72e-115: 356: 100.00
+	Hs
		241279 HNRC1_HUMAN (1-306): 2.22e-87: 265: 86.93		MATR3_HUMAN (71-364): 1.41e-59: 214: 20.64
+	Hs
		432590 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		MATR3_HUMAN (71-364): 1.41e-59: 214: 20.64
+	Hs
		540954 TRA2B_HUMAN (4-164): 1.14e-27: 110: 21.77		HNRPL_HUMAN (1-589): 5.72e-115: 356: 100.00
+	Hs
		432527 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		PABP1_HUMAN (53-384): 1.89e-42: 163: 16.19
+	Hs
		794171 RALY_HUMAN (2-298): 3.88e-63: 203: 40.19		MATR3_HUMAN (71-364): 1.41e-59: 214: 20.64
+	Hs
		241260 HNRC1_HUMAN (1-306): 2.22e-87: 265: 86.93		PAB4L_HUMAN (53-266): 1.13e-33: 133: 17.52
+	Hs
		432518 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		PAB4L_HUMAN (53-266): 1.13e-33: 133: 17.52
+	Mm
		665756 RALY_MOUSE (3-300): 1.41e-66: 212: 42.19		PABP1_MOUSE (53-384): 1.89e-42: 163: 16.48
+	Hs
		516734 RALY_HUMAN (2-298): 3.88e-63: 203: 40.19		PABP1_HUMAN (53-384): 1.89e-42: 163: 16.19
+	Hs
		320953 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		PTBP3_HUMAN (27-270): 2.6e-21: 99.7: 17.88
+	Hs
		432985 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		PTBP2_HUMAN (42-270): 4.52e-17: 86.3: 14.90
+	Hs
		794045 RB15B_HUMAN (9-292): 7.28e-31: 124: 12.03		MATR3_HUMAN (71-364): 1.41e-59: 214: 20.64
+	Hs
		432839 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		CELF1_HUMAN (196-275): 4.07e-11: 67.4: 20.00
+	Hs
		71198 HNRC2_HUMAN (1-306): 2.65e-80: 247: 84.64		CELF1_HUMAN (196-275): 4.07e-11: 67.4: 20.00
+	Hs
		321243 RALY_HUMAN (2-298): 3.88e-63: 203: 40.19		PTBP3_HUMAN (27-270): 2.6e-21: 99.7: 17.88
+	Hs
		516451 TRA2B_HUMAN (4-164): 1.14e-27: 110: 21.77		PABP1_HUMAN (53-384): 1.89e-42: 163: 16.19
+	Hs
		1272126 RALY_HUMAN (2-298): 3.88e-63: 203: 40.19		CELF1_HUMAN (196-275): 4.07e-11: 67.4: 20.00
+	Hs
		474017 SRSF3_HUMAN (9-93): 1.72e-26: 104: 30.68		PAB4L_HUMAN (53-266): 1.13e-33: 133: 17.52
+	Hs
		311355 A1CF_HUMAN (18-188): 1.71e-25: 108: 18.97		CELF2_HUMAN (196-275): 1.08e-10: 66.2: 17.65