HitPredict

Interactor 1: HNRPC (P07910)
Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1/C2)
Gene: HNRNPC

Interactor 2: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 306 Hs			1 499
+	Hs
		241281 HNRC1_HUMAN (1-306): 2.22e-87: 265: 86.93		CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00
+	Hs
		241282 HNRC1_HUMAN (1-306): 2.22e-87: 265: 86.93		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		432605 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		71086 HNRC2_HUMAN (1-306): 2.65e-80: 247: 84.64		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		71245 HNRC2_HUMAN (1-306): 2.65e-80: 247: 84.64		CLK4_HUMAN (1-484): 6.72e-136: 402: 55.05
+	Hs
		432550 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70
+	Hs
		432699 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Hs
		833938 SRS12_HUMAN (8-190): 2.14e-34: 127: 20.94		CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00
+	Hs
		833788 SRS12_HUMAN (8-190): 2.14e-34: 127: 20.94		CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31
+	Hs
		415100 RALY_HUMAN (2-298): 3.88e-63: 203: 40.19		CDK1_HUMAN (160-485): 3.05e-114: 340: 23.95
+	Hs
		833857 TRA2B_HUMAN (4-164): 1.14e-27: 110: 21.77		CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00
+	Hs
		833865 SRSF3_HUMAN (9-93): 1.72e-26: 104: 30.68		CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00
+	Hs
		834087 SRS12_HUMAN (8-190): 2.14e-34: 127: 20.94		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		1044256 RALY_HUMAN (2-298): 3.88e-63: 203: 40.19		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Hs
		833706 TRA2B_HUMAN (4-164): 1.14e-27: 110: 21.77		CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31
+	Hs
		833711 SRSF3_HUMAN (9-93): 1.72e-26: 104: 30.68		CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31
+	Hs
		834017 TRA2B_HUMAN (4-164): 1.14e-27: 110: 21.77		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Zm
		33400 A0A1D6M1U3_MAIZE (12-142): 1.38e-25: 106: 22.70		A0A1D6L2E7_MAIZE (43-486): 2.72e-110: 354: 28.16
+	Hs
		1043996 SRS12_HUMAN (8-190): 2.14e-34: 127: 20.94		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Hs
		925032 TRA2B_HUMAN (4-164): 1.14e-27: 110: 21.77		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50