HitPredict

Interactor 1: YES (P07947)
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)
Gene: YES1

Interactor 2: PECA1 (P16284)
Platelet endothelial cell adhesion molecule (PECAM-1) (EndoCAM) (GPIIA') (PECA1) (CD antigen CD31)
Gene: PECAM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	10858437
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0050731 - positive regulation of peptidyl-tyrosine phosphorylation GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 738
+	Hs
		522751 SRC_HUMAN (1-543): 0: 601: 74.22		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		411985 FYN_HUMAN (1-543): 0: 582: 72.16		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		442774 HCK_HUMAN (1-541): 0: 544: 57.49		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		411584 LCK_HUMAN (83-541): 0: 540: 60.78		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		433561 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		557441 ABL2_HUMAN (9-543): 9.27e-166: 503: 37.96		PECA1_HUMAN (1-738): 1.44e-140: 432: 100.00
+	Hs
		434019 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		ROBO2_HUMAN (11-737): 1.39e-82: 288: 12.20
+	Hs
		297881 FYN_HUMAN (1-543): 0: 582: 72.16		NFASC_HUMAN (292-736): 1.17e-37: 153: 12.71
+	Hs
		433804 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		SDK2_HUMAN (247-738): 8.87e-51: 194: 12.69
+	Hs
		433249 YES_HUMAN (1-543): 0: 617: 100.00		VCAM1_HUMAN (28-407): 7.14e-17: 86.9: 19.75
+	Mm
		639452 LYN_MOUSE (1-541): 1.19e-179: 517: 53.14		FCRL5_MOUSE (230-631): 2.04e-45: 173: 17.99
+	Hs
		433569 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		CD22_HUMAN (282-633): 8.62e-41: 162: 15.93
+	Hs
		434111 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		ROBO1_HUMAN (405-725): 5.45e-33: 139: 11.87
+	Hs
		297880 ABL1_HUMAN (41-543): 5.93e-161: 489: 39.10		NFASC_HUMAN (292-736): 1.17e-37: 153: 12.71
+	Hs
		433742 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		PTK7_HUMAN (8-235): 3.28e-27: 120: 12.45
+	Hs
		255429 LCK_HUMAN (83-541): 0: 540: 60.78		OBSL1_HUMAN (72-603): 1.4e-14: 80.3: 15.01