HitPredict

Interactor 1: YES (P07947)
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)
Gene: YES1

Interactor 2: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005884 - actin filament GO:0005886 - plasma membrane GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 205
+	Hs
		433475 YES_HUMAN (1-543): 0: 617: 100.00		RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59
+	Hs
		433322 YES_HUMAN (1-543): 0: 617: 100.00		RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97
+	Hs
		433314 YES_HUMAN (1-543): 0: 617: 100.00		RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98
+	Hs
		433305 YES_HUMAN (1-543): 0: 617: 100.00		CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57
+	Hs
		433307 YES_HUMAN (1-543): 0: 617: 100.00		RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75
+	Hs
		433239 YES_HUMAN (1-543): 0: 617: 100.00		RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03
+	Hs
		433304 YES_HUMAN (1-543): 0: 617: 100.00		RAC3_HUMAN (10-183): 9.1e-76: 227: 66.67
+	Hs
		433313 YES_HUMAN (1-543): 0: 617: 100.00		RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51
+	Hs
		433217 YES_HUMAN (1-543): 0: 617: 100.00		RHOC_HUMAN (1-192): 1.16e-74: 225: 50.52
+	Hs
		522888 SRC_HUMAN (1-543): 0: 601: 74.22		RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98
+	Hs
		522885 SRC_HUMAN (1-543): 0: 601: 74.22		RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51
+	Hs
		412123 FYN_HUMAN (1-543): 0: 582: 72.16		RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98
+	Hs
		412113 FYN_HUMAN (1-543): 0: 582: 72.16		CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57
+	Hs
		412115 FYN_HUMAN (1-543): 0: 582: 72.16		RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75
+	Hs
		411980 FYN_HUMAN (1-543): 0: 582: 72.16		RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03
+	Hs
		412120 FYN_HUMAN (1-543): 0: 582: 72.16		RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51
+	Hs
		411948 FYN_HUMAN (1-543): 0: 582: 72.16		RHOC_HUMAN (1-192): 1.16e-74: 225: 50.52
+	Hs
		433565 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00
+	Hs
		433556 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03
+	Hs
		433524 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		RHOC_HUMAN (1-192): 1.16e-74: 225: 50.52