HitPredict

Interactor 1: YES (P07947)
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)
Gene: YES1

Interactor 2: AFAD (P55196)
Afadin (ALL1-fused gene from chromosome 6 protein) (Protein AF-6) (Afadin adherens junction formation factor)
Gene: AFDN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 1824
+	Hs
		522873 SRC_HUMAN (1-543): 0: 601: 74.22		AFAD_HUMAN (1-1824): 0: 1279: 100.00
+	Hs
		433666 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		AFAD_HUMAN (1-1824): 0: 1279: 100.00
+	Hs
		433356 YES_HUMAN (1-543): 0: 617: 100.00		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Hs
		522995 SRC_HUMAN (1-543): 0: 601: 74.22		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Hs
		412200 FYN_HUMAN (1-543): 0: 582: 72.16		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Hs
		454833 FGR_HUMAN (1-542): 0: 562: 67.10		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Hs
		442832 HCK_HUMAN (1-541): 0: 544: 57.49		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Hs
		411726 LCK_HUMAN (83-541): 0: 540: 60.78		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Hs
		433768 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Mm
		403445 SRC_MOUSE (1-543): 0: 598: 73.67		DLG4_MOUSE (1002-1238): 8.46e-28: 123: 17.51
+	Hs
		986376 BTK_HUMAN (4-537): 1.03e-165: 487: 31.35		KIF14_HUMAN (179-624): 8.03e-59: 227: 18.67
+	Hs
		412128 FYN_HUMAN (1-543): 0: 582: 72.16		DLG4_HUMAN (1002-1238): 1.07e-27: 123: 17.51
+	Hs
		442887 HCK_HUMAN (1-541): 0: 544: 57.49		GOPC_HUMAN (744-1099): 5.55e-40: 157: 14.72
+	Hs
		411718 LCK_HUMAN (83-541): 0: 540: 60.78		SCRIB_HUMAN (989-1133): 4.27e-22: 106: 26.85
+	Hs
		411696 LCK_HUMAN (83-541): 0: 540: 60.78		PTN13_HUMAN (978-1122): 1.17e-17: 92.2: 29.14
+	Hs
		433758 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		SCRIB_HUMAN (989-1133): 4.27e-22: 106: 26.85
+	Hs
		434073 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		NEB1_HUMAN (1002-1092): 1.04e-19: 98.7: 40.00
+	Hs
		411905 LCK_HUMAN (83-541): 0: 540: 60.78		MYO5A_HUMAN (1369-1800): 2.36e-11: 71.5: 10.74
+	Hs
		433729 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		PTN13_HUMAN (978-1122): 1.17e-17: 92.2: 29.14
+	Dm
		113065 ABL_DROME (82-543): 1.38e-159: 496: 42.22		M9NFI9_DROME (1002-1092): 6.19e-22: 106: 38.95