HitPredict

Interactor 1: YES (P07947)
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)
Gene: YES1

Interactor 2: H90B3 (Q58FF7)
Putative heat shock protein HSP 90-beta-3 (Heat shock protein 90-beta c) (Heat shock protein 90Bc)
Gene: HSP90AB3P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	28514442, unassigned2173
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 597
+	Hs
		412223 FYN_HUMAN (1-543): 0: 582: 72.16		H90B3_HUMAN (1-597): 0: 838: 100.00
+	Hs
		433218 YES_HUMAN (1-543): 0: 617: 100.00		HS90B_HUMAN (1-597): 0: 799: 75.00
+	Hs
		431433 YES_HUMAN (1-543): 0: 617: 100.00		HS90A_HUMAN (1-597): 0: 798: 66.67
+	Hs
		437847 SRC_HUMAN (1-543): 0: 601: 74.22		HS90B_HUMAN (1-597): 0: 799: 75.00
+	Hs
		454838 FGR_HUMAN (1-542): 0: 562: 67.10		H90B3_HUMAN (1-597): 0: 838: 100.00
+	Hs
		431481 SRC_HUMAN (1-543): 0: 601: 74.22		HS90A_HUMAN (1-597): 0: 798: 66.67
+	Hs
		442841 HCK_HUMAN (1-541): 0: 544: 57.49		H90B3_HUMAN (1-597): 0: 838: 100.00
+	Hs
		411949 FYN_HUMAN (1-543): 0: 582: 72.16		HS90B_HUMAN (1-597): 0: 799: 75.00
+	Hs
		411945 FYN_HUMAN (1-543): 0: 582: 72.16		HS90A_HUMAN (1-597): 0: 798: 66.67
+	Hs
		437823 FGR_HUMAN (1-542): 0: 562: 67.10		HS90B_HUMAN (1-597): 0: 799: 75.00
+	Hs
		431451 FGR_HUMAN (1-542): 0: 562: 67.10		HS90A_HUMAN (1-597): 0: 798: 66.67
+	Hs
		437817 HCK_HUMAN (1-541): 0: 544: 57.49		HS90B_HUMAN (1-597): 0: 799: 75.00
+	Hs
		431445 HCK_HUMAN (1-541): 0: 544: 57.49		HS90A_HUMAN (1-597): 0: 798: 66.67
+	Hs
		411556 LCK_HUMAN (83-541): 0: 540: 60.78		HS90B_HUMAN (1-597): 0: 799: 75.00
+	Hs
		411551 LCK_HUMAN (83-541): 0: 540: 60.78		HS90A_HUMAN (1-597): 0: 798: 66.67
+	Hs
		411978 FYN_HUMAN (1-543): 0: 582: 72.16		ENPL_HUMAN (3-566): 0: 674: 37.68
+	Hs
		433378 YES_HUMAN (1-543): 0: 617: 100.00		H90B4_HUMAN (25-469): 9.6e-157: 460: 60.57
+	Hs
		412222 FYN_HUMAN (1-543): 0: 582: 72.16		H90B4_HUMAN (25-469): 9.6e-157: 460: 60.57
+	Hs
		433381 YES_HUMAN (1-543): 0: 617: 100.00		HS904_HUMAN (57-145): 3.15e-28: 119: 63.64
+	Hs
		412224 FYN_HUMAN (1-543): 0: 582: 72.16		HS904_HUMAN (57-145): 3.15e-28: 119: 63.64