HitPredict

Interactor 1: YES (P07947)
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)
Gene: YES1

Interactor 2: ANR54 (Q6NXT1)
Ankyrin repeat domain-containing protein 54 (Lyn-interacting ankyrin repeat protein)
Gene: ANKRD54

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 300
+	Hs
		523028 SRC_HUMAN (1-543): 0: 601: 74.22		ANR54_HUMAN (1-300): 7.42e-69: 217: 100.00
+	Hs
		411697 LCK_HUMAN (83-541): 0: 540: 60.78		ANK3_HUMAN (83-297): 6.75e-61: 211: 20.31
+	Hs
		411885 LCK_HUMAN (83-541): 0: 540: 60.78		KDIS_HUMAN (1-260): 6.37e-60: 208: 15.89
+	Mm
		639458 LYN_MOUSE (1-541): 1.19e-179: 517: 53.14		ANR54_MOUSE (1-300): 4.51e-70: 220: 92.00
+	Hs
		433832 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		ANR54_HUMAN (1-300): 7.42e-69: 217: 100.00
+	Hs
		433730 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		ANK3_HUMAN (83-297): 6.75e-61: 211: 20.31
+	Hs
		433701 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		ANK2_HUMAN (82-297): 7.44e-60: 208: 19.62
+	Hs
		434071 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		KDIS_HUMAN (1-260): 6.37e-60: 208: 15.89
+	Hs
		846484 BLK_HUMAN (66-538): 5.05e-174: 502: 59.07		ANR54_HUMAN (1-300): 7.42e-69: 217: 100.00
+	Hs
		986383 BTK_HUMAN (4-537): 1.03e-165: 487: 31.35		ANR54_HUMAN (1-300): 7.42e-69: 217: 100.00
+	Hs
		665439 EPHA3_HUMAN (3-535): 2.01e-156: 473: 25.84		KDIS_HUMAN (1-260): 6.37e-60: 208: 15.89
+	Mm
		976833 ITK_MOUSE (7-532): 3.88e-156: 461: 31.60		ANR54_MOUSE (1-300): 4.51e-70: 220: 92.00
+	Hs
		788998 TEC_HUMAN (7-535): 6.76e-156: 460: 32.96		ANR54_HUMAN (1-300): 7.42e-69: 217: 100.00
+	Hs
		434072 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		ANR50_HUMAN (124-297): 4.84e-39: 148: 21.17
+	Hs
		337406 ABL1_HUMAN (41-543): 5.93e-161: 489: 39.10		DAPK1_HUMAN (103-298): 1.54e-38: 146: 19.19
+	Dm
		337696 SRC64_DROME (1-542): 1.76e-173: 503: 46.57		TNKS_DROME (24-295): 3.24e-30: 121: 15.83