HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: EVL (Q9UI08)
Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein-like)
Gene: EVL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10945997
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0017124 - SH3 domain binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 512 Hs			1 416
+	Hs
		442892 HCK_HUMAN (1-512): 0: 595: 70.70		EVL_HUMAN (1-416): 1.85e-85: 268: 100.00
+	Hs
		523190 SRC_HUMAN (1-510): 0: 580: 51.97		EVL_HUMAN (1-416): 1.85e-85: 268: 100.00
+	Hs
		337581 ABL1_HUMAN (32-509): 9.04e-172: 516: 37.88		EVL_HUMAN (1-416): 1.85e-85: 268: 100.00
+	Hs
		433858 LYN_HUMAN (1-512): 0: 611: 100.00		SPRE1_HUMAN (2-165): 1.31e-48: 173: 26.74
+	Hs
		433948 LYN_HUMAN (1-512): 0: 611: 100.00		ASPP1_HUMAN (80-367): 2.59e-35: 140: 18.62
+	Hs
		412242 FYN_HUMAN (1-510): 0: 576: 54.12		SPRE1_HUMAN (2-165): 1.31e-48: 173: 26.74
+	Hs
		279832 LYN_HUMAN (1-512): 0: 611: 100.00		TRIO_HUMAN (135-408): 7.1e-30: 124: 13.48
+	Hs
		411823 LCK_HUMAN (1-512): 0: 582: 63.62		ASPP1_HUMAN (80-367): 2.59e-35: 140: 18.62
+	Ce
		106631 SRC1_CAEEL (1-511): 3.84e-176: 507: 42.29		G5EG53_CAEEL (2-405): 6.58e-64: 214: 22.60
+	Hs
		279830 LCK_HUMAN (1-512): 0: 582: 63.62		TRIO_HUMAN (135-408): 7.1e-30: 124: 13.48
+	Hs
		297808 LYN_HUMAN (1-512): 0: 611: 100.00		K0754_HUMAN (95-390): 7.09e-20: 94.7: 12.26
+	Dm
		337658 ABL_DROME (3-508): 3.3e-170: 523: 36.36		ENA_DROME (2-386): 1.01e-40: 156: 24.68
+	Ce
		106638 SRC1_CAEEL (1-511): 3.84e-176: 507: 42.29		H2L0C7_CAEEL (14-171): 4.53e-44: 157: 23.84
+	Hs
		203198 LCK_HUMAN (1-512): 0: 582: 63.62		SYNJ1_HUMAN (94-376): 2.64e-09: 61.6: 8.78
+	Mm
		403433 SRC_MOUSE (1-510): 0: 577: 52.07		ENAH_MOUSE (98-415): 5.28e-11: 66.6: 32.72
+	Mm
		763387 FYN_MOUSE (1-510): 0: 576: 53.93		ENAH_MOUSE (98-415): 5.28e-11: 66.6: 32.72
+	Mm
		337626 ABL1_MOUSE (32-509): 5.71e-172: 516: 37.88		ENAH_MOUSE (98-415): 5.28e-11: 66.6: 32.72