Interactor 1: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET
Interactor 2: SOS1 (Q07889)
Son of sevenless homolog 1 (SOS-1)
Gene: SOS1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.33 | 1.00 | 0.575 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19914172 |
| Identification Methods | anti bait coimmunoprecipitation |
| Interaction Type | association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~PK_Tyr_Ser-Thr |
| Common GO terms | GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0007411 - axon guidance GO:0043025 - neuronal cell body |
| Homologous interactions | 18 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
