Interactor 1: TSP1 (P07996)
Thrombospondin-1 (Glycoprotein G)
Gene: THBS1

Interactor 2: MMP2 (P08253)
72 kDa type IV collagenase (EC 3.4.24.24) (72 kDa gelatinase) (Gelatinase A) (Matrix metalloproteinase-2) (MMP-2) (TBE-1) [Cleaved into: PEX]
Gene: MMP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 0.60 0.552

The method score is based on:

Property Details
Experiments 10900205
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001666 - response to hypoxia
GO:0001968 - fibronectin binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0009410 - response to xenobiotic stimulus
and 3 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 1170
Hs

1 660
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024