Protein: RL22L
Ribosomal protein eL22-like (60S ribosomal protein L22-like 1) (Large ribosomal subunit protein eL22-like 1)

Gene: RL22L, RPL22L1
Organism: Homo sapiens
Interactions: 79
UniProt ID: Q6P5R6

Gene Ontology (top 5):
GO:0002181 - cytoplasmic translation
GO:0003723 - RNA binding
GO:0003735 - structural constituent of ribosome
GO:0005840 - ribosome
GO:1990904 - ribonucleoprotein complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1242792

G3BP2
Ras GTPase-activating protein-binding protein 2

2

4

High-throughput

0.628

High

987711

GRB2
Growth factor receptor-bound protein 2

2

3

High-throughput

0.571

High

1242783

SDCB2
Syntenin-2

2

2

High-throughput

0.553

High

951720

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

2

1

Small-scale

0.550

High

447124

NPM
Nucleophosmin

1

2

High-throughput

0.536

High

529970

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.536

High

859325

RL5
Large ribosomal subunit protein uL18

1

3

High-throughput

0.536

High

985719

RL11
Large ribosomal subunit protein uL5

1

4

High-throughput

0.536

High

1089718

ILF3
Interleukin enhancer-binding factor 3

1

4

High-throughput

0.536

High

1242787

SRP68
Signal recognition particle subunit SRP68

1

1

High-throughput

0.536

High

1242793

DRG1
Developmentally-regulated GTP-binding protein 1

1

3

High-throughput

0.536

High

372330

MYC
Myc proto-oncogene protein

2

3

High-throughput

0.533

High

1242779

DDRGK
DDRGK domain-containing protein 1

2

1

Small-scale

0.533

High

440121

LCK
Tyrosine-protein kinase Lck

2

1

High-throughput

0.521

High

541553

FGFR1
Fibroblast growth factor receptor 1

2

1

High-throughput

0.521

High

1097099

MP2K5
Dual specificity mitogen-activated protein kinase kinase 5

2

1

High-throughput

0.521

High

1144530

PTPRR
Receptor-type tyrosine-protein phosphatase R

2

2

High-throughput

0.521

High

1242767

RHG36
Rho GTPase-activating protein 36

2

1

High-throughput

0.521

High

679193

DNJB1
DnaJ homolog subfamily B member 1

1

1

High-throughput

0.489

High

1199422

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

1

High-throughput

0.489

High

1242771

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.489

High

134777

SAP18
Histone deacetylase complex subunit SAP18

1

1

High-throughput

0.479

High

345958

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

5

High-throughput

0.479

High

1138323

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1215670

RC3H1
Roquin-1

1

2

High-throughput

0.479

High

1242766

GGYF2
GRB10-interacting GYF protein 2

1

2

Small-scale

0.479

High

1242770

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

5

High-throughput

0.479

High

1242782

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

132105

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

4

High-throughput

0.437

High

178299

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.437

High

238542

RAD21
Double-strand-break repair protein rad21 homolog

1

1

High-throughput

0.437

High

299555

TRIO
Triple functional domain protein

1

1

High-throughput

0.437

High

319848

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.437

High

406292

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.437

High

576240

PO2F1
POU domain, class 2, transcription factor 1

1

1

Small-scale

0.437

High

584557

VAV
Proto-oncogene vav

1

4

High-throughput

0.437

High

606859

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.437

High

711141

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

2

High-throughput

0.437

High

879198

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

888134

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.437

High

897312

CDK7
Cyclin-dependent kinase 7

1

3

High-throughput

0.437

High

937788

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.437

High

1028244

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

High-throughput

0.437

High

1035706

KIF23
Kinesin-like protein KIF23

1

2

High-throughput

0.437

High

1045411

TF65
Transcription factor p65

1

1

High-throughput

0.437

High

1091817

TP4A2
Protein tyrosine phosphatase type IVA 2

1

2

High-throughput

0.437

High

1137782

TNIP1
TNFAIP3-interacting protein 1

1

6

High-throughput

0.437

High

1140434

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.437

High

1201836

PKHG4
Puratrophin-1

1

3

High-throughput

0.437

High

1218584

OTU1
Ubiquitin thioesterase OTU1

1

1

High-throughput

0.437

High

1242768

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

1242772

LDHD
Probable D-lactate dehydrogenase, mitochondrial

1

1

High-throughput

0.437

High

1242775

TIP
T-cell immunomodulatory protein

1

1

High-throughput

0.437

High

1242776

STAR8
StAR-related lipid transfer protein 8

1

1

High-throughput

0.437

High

1242781

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

1242784

ANLN
Anillin

1

2

High-throughput

0.437

High

1242786

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

1242789

XPO7
Exportin-7

1

1

High-throughput

0.437

High

1242790

PKHG1
Pleckstrin homology domain-containing family G member 1

1

3

High-throughput

0.437

High

1242791

FZR1
Fizzy-related protein homolog

1

5

High-throughput

0.437

High

1242794

LOXL2
Lysyl oxidase homolog 2

1

1

High-throughput

0.437

High

516538

CALM3
Calmodulin-3

1

1

High-throughput

0.407

High

1132378

CASP8
Caspase-8

1

1

High-throughput

0.407

High

1179409

VMAC
Vimentin-type intermediate filament-associated coiled-coil protein

3

0

High-throughput

0.342

High

1242778

T3HPD
Trans-3-hydroxy-L-proline dehydratase

3

0

High-throughput

0.342

High

1081744

FP100
Fanconi anemia core complex-associated protein 100

2

0

High-throughput

0.318

High

1154527

CC85B
Coiled-coil domain-containing protein 85B

2

0

High-throughput

0.318

High

1163840

DUS6
Dual specificity protein phosphatase 6

2

0

High-throughput

0.298

High

342223

BRD1
Bromodomain-containing protein 1

1

0

Small-scale

0.279

Low

1242769

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.279

Low

1242788

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.279

Low

293869

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

1218374

ARHGG
Rho guanine nucleotide exchange factor 16

1

0

High-throughput

0.249

Low

1242773

DOCK4
Dedicator of cytokinesis protein 4

1

0

High-throughput

0.249

Low

1242774

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.249

Low

1242777

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.249

Low

1242780

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.249

Low

1242785

KS6B2
Ribosomal protein S6 kinase beta-2

1

0

High-throughput

0.249

Low

1242795

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025