HitPredict - High confidence protein-protein interactions

Interactor 1: EGR1 (P08046)
Early growth response protein 1 (EGR-1) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor Zif268) (Zinc finger protein Krox-24)
Gene: EGR1

Interactor 2: SRF (Q9JM73)
Serum response factor (SRF)
Gene: SRF

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	19417216, 15749018, 12496415
Identification Methods	anti tag coimmunoprecipitation, electrophoretic mobility supershift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001666 - response to hypoxia and 11 others more... GO:0003677 - DNA binding GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0006355 - regulation of DNA-templated transcription GO:0007616 - long-term memory GO:0043565 - sequence-specific DNA binding GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:1902895 - positive regulation of miRNA transcription
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	533
Mm

1	504

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024