HitPredict

Interactor 1: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Interactor 2: RAB21 (Q9UL25)
Ras-related protein Rab-21
Gene: RAB21

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1367 Hs			1 225
+	Hs
		435598 IGF1R_HUMAN (1-1367): 0: 1387: 100.00		RB11A_HUMAN (9-224): 6.96e-85: 252: 32.41
+	Rn
		69428 INSR_RAT (20-1365): 0: 1210: 55.45		B0BMW0_RAT (10-221): 5.83e-96: 280: 33.95
+	Hs
		411350 INSR_HUMAN (32-1365): 0: 1219: 56.54		RB11A_HUMAN (9-224): 6.96e-85: 252: 32.41
+	Rn
		102471 INSR_RAT (20-1365): 0: 1210: 55.45		G3V6H0_RAT (12-222): 6.9e-85: 252: 30.33
+	Rn
		192819 INSR_RAT (20-1365): 0: 1210: 55.45		RB11B_RAT (9-224): 1e-84: 252: 32.72
+	Rn
		544805 INSR_RAT (20-1365): 0: 1210: 55.45		RB11A_RAT (9-224): 6.96e-85: 252: 32.41
+	Hs
		411339 INSR_HUMAN (32-1365): 0: 1219: 56.54		RAB5C_HUMAN (1-224): 1.01e-51: 168: 39.82
+	Rn
		69451 INSR_RAT (20-1365): 0: 1210: 55.45		B0BNK1_RAT (1-224): 2.56e-51: 167: 39.82
+	Rn
		69430 INSR_RAT (20-1365): 0: 1210: 55.45		B0BN19_RAT (20-203): 1.62e-44: 149: 43.32
+	Rn
		544790 INSR_RAT (20-1365): 0: 1210: 55.45		RAB8A_RAT (18-221): 1.21e-42: 144: 38.24
+	Hs
		537727 INSRR_HUMAN (14-1310): 0: 1170: 55.26		RAB13_HUMAN (20-200): 1.67e-42: 144: 38.67
+	Hs
		665466 EPHA8_HUMAN (655-1337): 4.83e-169: 533: 23.87		RB11A_HUMAN (9-224): 6.96e-85: 252: 32.41
+	Hs
		665197 EPHA2_HUMAN (653-1304): 6.11e-163: 516: 23.93		RB11A_HUMAN (9-224): 6.96e-85: 252: 32.41
+	Hs
		665173 EPHA2_HUMAN (653-1304): 6.11e-163: 516: 23.93		RAB5C_HUMAN (1-224): 1.01e-51: 168: 39.82
+	Hs
		592117 EPHA2_HUMAN (653-1304): 6.11e-163: 516: 23.93		RAB5A_HUMAN (10-224): 2.26e-49: 162: 41.28
+	Hs
		666566 LTK_HUMAN (989-1319): 5.64e-75: 270: 40.11		RAB8A_HUMAN (13-221): 7.3e-97: 282: 37.32
+	Hs
		666646 LTK_HUMAN (989-1319): 5.64e-75: 270: 40.11		RAB1B_HUMAN (12-222): 1.28e-85: 254: 30.81
+	Hs
		666630 LTK_HUMAN (989-1319): 5.64e-75: 270: 40.11		RAB1C_HUMAN (12-222): 1.46e-82: 246: 30.33
+	Hs
		384608 NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61		RB11A_HUMAN (9-224): 6.96e-85: 252: 32.41
+	Hs
		384514 NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61		RAB5C_HUMAN (1-224): 1.01e-51: 168: 39.82