HitPredict

Interactor 1: CO3A1 (P08121)
Collagen alpha-1(III) chain
Gene: Col3a1

Interactor 2: SMAD3 (Q8BUN5)
Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (mMad3) (SMAD family member 3) (SMAD 3) (Smad3)
Gene: SMAD3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14559231
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001701 - in utero embryonic development GO:0007179 - transforming growth factor beta receptor signaling pathway GO:1990776 - response to angiotensin
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1464 Mm			1 425
+	Mm
		503178 CO1A1_MOUSE (25-1464): 0: 652: 59.40		SMAD3_MOUSE (1-425): 0: 636: 100.00
+	Hs
		358494 CO1A1_HUMAN (24-1464): 0: 638: 60.47		SMAD3_HUMAN (1-425): 0: 636: 100.00
+	Mm
		503177 CO1A1_MOUSE (25-1464): 0: 652: 59.40		SMAD2_MOUSE (1-425): 0: 591: 83.73
+	Hs
		358519 CO1A1_HUMAN (24-1464): 0: 638: 60.47		SMAD2_HUMAN (1-425): 0: 589: 83.73
+	Mm
		435995 CO3A1_MOUSE (1-1464): 0: 586: 99.59		SMAD2_MOUSE (1-425): 0: 591: 83.73
+	Mm
		435992 CO3A1_MOUSE (1-1464): 0: 586: 99.59		SMAD1_MOUSE (1-425): 0: 560: 59.87
+	Mm
		503173 CO1A1_MOUSE (25-1464): 0: 652: 59.40		SMAD4_MOUSE (23-414): 2.27e-119: 360: 32.88
+	Hs
		358510 CO1A1_HUMAN (24-1464): 0: 638: 60.47		SMAD4_HUMAN (23-414): 1.55e-117: 355: 33.21
+	Mm
		192481 CO1A1_MOUSE (25-1464): 0: 652: 59.40		SMAD7_MOUSE (28-403): 8.69e-99: 303: 27.06
+	Mm
		435994 CO3A1_MOUSE (1-1464): 0: 586: 99.59		SMAD4_MOUSE (23-414): 2.27e-119: 360: 32.88
+	Mm
		192480 CO3A1_MOUSE (1-1464): 0: 586: 99.59		SMAD7_MOUSE (28-403): 8.69e-99: 303: 27.06
+	Mm
		291326 CO5A1_MOUSE (18-486): 1.25e-23: 111: 36.89		SMAD3_MOUSE (1-425): 0: 636: 100.00
+	Mm
		291325 CO5A1_MOUSE (18-486): 1.25e-23: 111: 36.89		SMAD2_MOUSE (1-425): 0: 591: 83.73
+	Mm
		291322 CO5A1_MOUSE (18-486): 1.25e-23: 111: 36.89		SMAD1_MOUSE (1-425): 0: 560: 59.87
+	Mm
		291323 CO5A1_MOUSE (18-486): 1.25e-23: 111: 36.89		SMAD4_MOUSE (23-414): 2.27e-119: 360: 32.88
+	Mm
		192478 CO5A1_MOUSE (18-486): 1.25e-23: 111: 36.89		SMAD7_MOUSE (28-403): 8.69e-99: 303: 27.06