HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: GNAS2 (P63092)
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Adenylate cyclase-stimulating G alpha protein)
Gene: GNAS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34285210, 31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 394
+	Hs
		900360 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		GNAS2_HUMAN (1-394): 1.94e-179: 506: 100.00
+	Hs
		925172 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		GNAS2_HUMAN (1-394): 1.94e-179: 506: 100.00
+	Hs
		926567 RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92		GNAS2_HUMAN (1-394): 1.94e-179: 506: 100.00
+	Hs
		893881 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		GNAS2_HUMAN (1-394): 1.94e-179: 506: 100.00
+	Hs
		915590 RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82		GNAS2_HUMAN (1-394): 1.94e-179: 506: 100.00
+	Hs
		892308 RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54		GNAS2_HUMAN (1-394): 1.94e-179: 506: 100.00
+	Hs
		391369 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		GNAI2_HUMAN (1-394): 1.99e-158: 451: 38.83
+	Hs
		391375 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		GNAI2_HUMAN (1-394): 1.99e-158: 451: 38.83
+	Hs
		391307 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		GNAI2_HUMAN (1-394): 1.99e-158: 451: 38.83
+	Hs
		436127 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		GNAI3_HUMAN (1-394): 1.06e-155: 444: 38.58
+	Hs
		391372 RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82		GNAI2_HUMAN (1-394): 1.99e-158: 451: 38.83
+	Hs
		670448 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		GNA11_HUMAN (11-394): 1.04e-146: 421: 38.80
+	Hs
		670452 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		GNA11_HUMAN (11-394): 1.04e-146: 421: 38.80
+	Hs
		436171 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		GNA11_HUMAN (11-394): 1.04e-146: 421: 38.80
+	Hs
		670445 CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30		GNA11_HUMAN (11-394): 1.04e-146: 421: 38.80
+	Hs
		670450 RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82		GNA11_HUMAN (11-394): 1.04e-146: 421: 38.80
+	Hs
		670444 RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54		GNA11_HUMAN (11-394): 1.04e-146: 421: 38.80