HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: IQGA3 (Q86VI3)
Ras GTPase-activating-like protein IQGAP3
Gene: IQGAP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RasGAP
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1631
+	Hs
		900647 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		IQGA3_HUMAN (1-1631): 0: 1709: 100.00
+	Hs
		925404 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		IQGA3_HUMAN (1-1631): 0: 1709: 100.00
+	Hs
		809241 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		IQGA1_HUMAN (6-1631): 0: 1574: 58.99
+	Hs
		809255 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		IQGA1_HUMAN (6-1631): 0: 1574: 58.99
+	Hs
		436197 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		IQGA1_HUMAN (6-1631): 0: 1574: 58.99
+	Mm
		925821 RAC1_MOUSE (1-193): 7.23e-81: 240: 57.22		IQGA1_MOUSE (7-1631): 0: 1543: 58.85
+	Hs
		925259 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		IQGA2_HUMAN (86-1631): 0: 1356: 42.50
+	Dd
		136239 RAC1A_DICDI (1-193): 2.24e-78: 233: 54.08		GAPA_DICDI (828-1630): 3.05e-136: 445: 25.98
+	Hs
		925282 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		RASA3_HUMAN (841-1504): 2.12e-105: 359: 13.68
+	Hs
		925728 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		MYO5B_HUMAN (696-1522): 2.83e-96: 346: 14.42
+	Hs
		901032 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		NGAP_HUMAN (1000-1453): 5.22e-81: 294: 17.18
+	Hs
		925715 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		NGAP_HUMAN (1000-1453): 5.22e-81: 294: 17.18
+	Hs
		436564 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		NGAP_HUMAN (1000-1453): 5.22e-81: 294: 17.18
+	Gg
		1141019 Q6LC82_CHICK (1-193): 7.23e-81: 240: 57.22		ARHG6_CHICK (37-448): 7.38e-77: 274: 11.83
+	Hs
		925347 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		DAB2P_HUMAN (1000-1424): 2.56e-68: 255: 15.03
+	Hs
		900814 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		SYGP1_HUMAN (1000-1345): 1.08e-65: 247: 16.44
+	Hs
		925530 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		SYGP1_HUMAN (1000-1345): 1.08e-65: 247: 16.44
+	Hs
		436465 RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00		SYGP1_HUMAN (1000-1345): 1.08e-65: 247: 16.44
+	Hs
		598453 RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71		NF1_HUMAN (967-1301): 9.74e-45: 181: 21.57
+	Hs
		598457 RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22		NF1_HUMAN (967-1301): 9.74e-45: 181: 21.57