HitPredict

Interactor 1: UBL4A (P11441)
Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
Gene: UBL4A

Interactor 2: KPCA (P17252)
Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)
Gene: PRKCA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 157 Hs			1 672
+	Hs
		475314 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		KPCA_HUMAN (1-672): 0: 794: 100.00
+	Rn
		934619 UBC_RAT (1-102): 9.46e-29: 112: 31.13		KPCB_RAT (1-664): 0: 747: 79.34
+	Hs
		408534 UBB_HUMAN (1-76): 1.43e-29: 109: 39.47		KPCB_HUMAN (1-664): 0: 749: 78.89
+	Hs
		408535 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		KPCB_HUMAN (1-664): 0: 749: 78.89
+	Hs
		408593 RL40_HUMAN (1-72): 8.53e-30: 106: 41.67		KPCB_HUMAN (1-664): 0: 749: 78.89
+	Rn
		930581 UBC_RAT (1-102): 9.46e-29: 112: 31.13		KPCG_RAT (16-670): 0: 698: 69.88
+	Hs
		923962 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		KPCE_HUMAN (8-664): 0: 635: 44.61
+	Rn
		448416 UBC_RAT (1-102): 9.46e-29: 112: 31.13		KPCE_RAT (8-664): 0: 631: 44.31
+	Hs
		681773 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		AKT1_HUMAN (243-660): 2.07e-155: 459: 37.36
+	Hs
		474935 UBB_HUMAN (1-76): 1.43e-29: 109: 39.47		AKT1_HUMAN (243-660): 2.07e-155: 459: 37.36
+	Hs
		474936 UBB_HUMAN (1-76): 1.43e-29: 109: 39.47		AKT2_HUMAN (242-660): 9.73e-156: 459: 39.13
+	Hs
		475390 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		AKT1_HUMAN (243-660): 2.07e-155: 459: 37.36
+	Hs
		681774 RL40_HUMAN (1-72): 8.53e-30: 106: 41.67		AKT1_HUMAN (243-660): 2.07e-155: 459: 37.36
+	Hs
		116959 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		SGK1_HUMAN (255-661): 1.16e-153: 452: 38.85
+	Rn
		448410 UBC_RAT (1-102): 9.46e-29: 112: 31.13		KPCD_RAT (9-175): 2.83e-56: 204: 37.29
+	Mm
		476830 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		KPCI_MOUSE (22-108): 6.42e-34: 139: 36.78
+	Hs
		475450 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		KPCI_HUMAN (22-86): 8.63e-12: 70.1: 43.08
+	Hs
		475653 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		KPCZ_HUMAN (22-98): 3.2e-11: 68.6: 34.44