Interactor 1: HEPS (P05981)
Serine protease hepsin (EC 3.4.21.106) (Transmembrane protease serine 1) [Cleaved into: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain]
Gene: HPN

Interactor 2: ANKL2 (Q86XL3)
Ankyrin repeat and LEM domain-containing protein 2 (LEM domain-containing protein 4)
Gene: ANKLE2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments unassigned3799
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0016020 - membrane
GO:0043066 - negative regulation of apoptotic process
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 417
Hs

1 938
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025