HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: NFIC (P08651)
Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein)
Gene: NFIC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22939624
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 508
+	Hs
		431446 HS90A_HUMAN (1-724): 0: 1072: 85.25		NFIC_HUMAN (1-508): 1.61e-162: 472: 100.00
+	Hs
		437954 HS90B_HUMAN (1-724): 0: 1086: 100.00		SRBP1_HUMAN (293-455): 4.43e-21: 99.2: 15.06
+	Hs
		431605 HS90A_HUMAN (1-724): 0: 1072: 85.25		SRBP1_HUMAN (293-455): 4.43e-21: 99.2: 15.06
+	Hs
		438364 HS90B_HUMAN (1-724): 0: 1086: 100.00		KMT2C_HUMAN (177-499): 7.42e-09: 60.7: 11.98
+	Hs
		438426 HS90B_HUMAN (1-724): 0: 1086: 100.00		KLH29_HUMAN (189-427): 5.65e-09: 60.7: 10.20
+	Hs
		432143 HS90A_HUMAN (1-724): 0: 1072: 85.25		KLH29_HUMAN (189-427): 5.65e-09: 60.7: 10.20
+	Sc
		366285 HSP82_YEAST (12-724): 0: 927: 61.26		SEC31_YEAST (184-421): 1.2e-09: 63: 11.89
+	Sc
		543728 HSC82_YEAST (13-724): 0: 922: 60.22		SEC31_YEAST (184-421): 1.2e-09: 63: 11.89