Protein: TMPS3
Transmembrane protease serine 3 (EC 3.4.21.-) (Serine protease TADG-12) (Tumor-associated differentially-expressed gene 12 protein)

Gene: TMPS3, TMPRSS3
Organism: Homo sapiens
Interactions: 35
UniProt ID: P57727

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006508 - proteolysis
GO:0006883 - intracellular sodium ion homeostasis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

944920

LRP10
Low-density lipoprotein receptor-related protein 10

2

12

High-throughput

0.811

High

944919

LRIG3
Leucine-rich repeats and immunoglobulin-like domains protein 3

2

12

High-throughput

0.726

High

944924

NETO2
Neuropilin and tolloid-like protein 2

2

13

High-throughput

0.726

High

944928

LRFN3
Leucine-rich repeat and fibronectin type-III domain-containing protein 3

2

11

High-throughput

0.726

High

409330

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

12

High-throughput

0.691

High

603909

CXA1
Gap junction alpha-1 protein

2

2

High-throughput

0.628

High

611059

PTN1
Tyrosine-protein phosphatase non-receptor type 1

2

10

High-throughput

0.628

High

944917

RETST
All-trans-retinol 13,14-reductase

2

1

High-throughput

0.628

High

944921

VRK2
Serine/threonine-protein kinase VRK2

2

7

High-throughput

0.628

High

944922

K319L
Dyslexia-associated protein KIAA0319-like protein

2

5

High-throughput

0.628

High

944923

CISD2
CDGSH iron-sulfur domain-containing protein 2

2

1

High-throughput

0.628

High

944925

PDZD8
PDZ domain-containing protein 8

2

2

High-throughput

0.628

High

944926

DCAKD
Dephospho-CoA kinase domain-containing protein

2

1

High-throughput

0.628

High

944927

CGRF1
Cell growth regulator with RING finger domain protein 1

2

2

High-throughput

0.628

High

944929

TOR3A
Torsin-3A

2

13

High-throughput

0.628

High

944930

ALG9
Alpha-1,2-mannosyltransferase ALG9

2

5

High-throughput

0.628

High

944931

DJC18
DnaJ homolog subfamily C member 18

2

8

High-throughput

0.628

High

944934

E2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3

2

6

High-throughput

0.628

High

944935

DHRS7
Dehydrogenase/reductase SDR family member 7

2

4

High-throughput

0.628

High

72653

UPK3L
Uroplakin-3b-like protein 1

2

0

High-throughput

0.602

High

944914

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

2

0

High-throughput

0.602

High

931924

EPHB4
Ephrin type-B receptor 4

2

17

High-throughput

0.574

High

944936

TMED7
Transmembrane emp24 domain-containing protein 7

1

2

High-throughput

0.541

High

61097

T131L
Transmembrane protein 131-like

1

1

High-throughput

0.536

High

161013

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

19

High-throughput

0.536

High

698535

CALX
Calnexin

1

13

High-throughput

0.536

High

944932

TM39A
Transmembrane protein 39A

1

1

High-throughput

0.536

High

944916

PR15B
Protein phosphatase 1 regulatory subunit 15B

2

0

High-throughput

0.528

High

944913

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.518

High

122742

KIF2A
Kinesin-like protein KIF2A

1

0

High-throughput

0.513

High

944915

S27A3
Long-chain fatty acid transport protein 3

1

0

High-throughput

0.513

High

625792

RXRA
Retinoic acid receptor RXR-alpha

1

3

High-throughput

0.494

High

175341

PLXB2
Plexin-B2

1

18

High-throughput

0.489

High

944918

ZNT6
Zinc transporter 6

1

1

High-throughput

0.489

High

944933

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

1

3

High-throughput

0.489

High


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Last updated: 11Aug2025