HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: VDR (P11473)
Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor) (Nuclear receptor subfamily 1 group I member 1)
Gene: VDR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25910212
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 724 Hs			1 427
+	Mm
		193208 HS90B_MOUSE (1-724): 0: 1089: 99.59		NR1I3_MOUSE (4-421): 3.85e-107: 322: 34.21
+	Hs
		438177 HS90B_HUMAN (1-724): 0: 1086: 100.00		NR1I3_HUMAN (17-421): 5.58e-108: 324: 33.66
+	Hs
		431858 HS90A_HUMAN (1-724): 0: 1072: 85.25		NR1I3_HUMAN (17-421): 5.58e-108: 324: 33.66
+	Hs
		437985 HS90B_HUMAN (1-724): 0: 1086: 100.00		NR2C2_HUMAN (16-427): 7.44e-97: 303: 19.71
+	Hs
		437955 HS90B_HUMAN (1-724): 0: 1086: 100.00		PPARG_HUMAN (11-424): 5.91e-96: 298: 25.60
+	Hs
		368839 HS90B_HUMAN (1-724): 0: 1086: 100.00		ESR1_HUMAN (2-425): 4.59e-94: 296: 20.74
+	Hs
		438124 HS90B_HUMAN (1-724): 0: 1086: 100.00		NR1H3_HUMAN (2-425): 7.16e-95: 294: 29.60
+	Hs
		438091 HS90B_HUMAN (1-724): 0: 1086: 100.00		PPARD_HUMAN (19-424): 2.02e-93: 290: 24.88
+	Hs
		431647 HS90A_HUMAN (1-724): 0: 1072: 85.25		NR2C2_HUMAN (16-427): 7.44e-97: 303: 19.71
+	Hs
		431608 HS90A_HUMAN (1-724): 0: 1072: 85.25		PPARG_HUMAN (11-424): 5.91e-96: 298: 25.60
+	Hs
		265846 HS90B_HUMAN (1-724): 0: 1086: 100.00		NR1I2_HUMAN (2-422): 1.41e-90: 282: 39.62
+	Hs
		368832 HS90A_HUMAN (1-724): 0: 1072: 85.25		ESR1_HUMAN (2-425): 4.59e-94: 296: 20.74
+	Hs
		431801 HS90A_HUMAN (1-724): 0: 1072: 85.25		NR1H3_HUMAN (2-425): 7.16e-95: 294: 29.60
+	Hs
		437901 HS90B_HUMAN (1-724): 0: 1086: 100.00		NR4A1_HUMAN (8-426): 5.04e-88: 280: 21.00
+	Hs
		320158 HS90B_HUMAN (1-724): 0: 1086: 100.00		ERR2_HUMAN (8-426): 3.98e-88: 276: 20.53
+	Hs
		431759 HS90A_HUMAN (1-724): 0: 1072: 85.25		PPARD_HUMAN (19-424): 2.02e-93: 290: 24.88
+	Hs
		265845 HS90A_HUMAN (1-724): 0: 1072: 85.25		NR1I2_HUMAN (2-422): 1.41e-90: 282: 39.62
+	Hs
		320155 HS90A_HUMAN (1-724): 0: 1072: 85.25		ERR2_HUMAN (8-426): 3.98e-88: 276: 20.53
+	Hs
		431775 HS90A_HUMAN (1-724): 0: 1072: 85.25		PPARA_HUMAN (1-424): 6.31e-88: 276: 23.67
+	Hs
		368916 ENPL_HUMAN (3-693): 0: 917: 46.44		ESR1_HUMAN (2-425): 4.59e-94: 296: 20.74