HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: NR4A1 (P22736)
Nuclear receptor subfamily 4immunitygroup A member 1 (Early response protein NAK1) (Nuclear hormone receptor NUR/77) (Nur77) (Orphan nuclear receptor HMR) (Orphan nuclear receptor TR3) (ST-59) (Testicular receptor 3)
Gene: NR4A1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 724 Hs			1 598
+	Hs
		438124 HS90B_HUMAN (1-724): 0: 1086: 100.00		NR1H3_HUMAN (178-591): 7.99e-114: 348: 29.29
+	Hs
		431801 HS90A_HUMAN (1-724): 0: 1072: 85.25		NR1H3_HUMAN (178-591): 7.99e-114: 348: 29.29
+	Hs
		437625 HS90B_HUMAN (1-724): 0: 1086: 100.00		MCR_HUMAN (2-597): 2.28e-101: 331: 19.57
+	Hs
		431775 HS90A_HUMAN (1-724): 0: 1072: 85.25		PPARA_HUMAN (212-595): 3.12e-111: 342: 23.62
+	Hs
		320158 HS90B_HUMAN (1-724): 0: 1086: 100.00		ERR2_HUMAN (184-594): 1.46e-103: 321: 28.02
+	Hs
		431441 HS90A_HUMAN (1-724): 0: 1072: 85.25		MCR_HUMAN (2-597): 2.28e-101: 331: 19.57
+	Hs
		368839 HS90B_HUMAN (1-724): 0: 1086: 100.00		ESR1_HUMAN (61-592): 2.41e-97: 311: 22.79
+	Hs
		437955 HS90B_HUMAN (1-724): 0: 1086: 100.00		PPARG_HUMAN (120-594): 8.32e-99: 311: 21.55
+	Mm
		415154 HS90B_MOUSE (1-724): 0: 1089: 99.59		GCR_MOUSE (21-597): 3.11e-93: 305: 22.17
+	Hs
		320155 HS90A_HUMAN (1-724): 0: 1072: 85.25		ERR2_HUMAN (184-594): 1.46e-103: 321: 28.02
+	Hs
		377022 HS90B_HUMAN (1-724): 0: 1086: 100.00		GCR_HUMAN (21-597): 6.09e-93: 304: 22.09
+	Rn
		415133 HS90B_RAT (1-724): 0: 1089: 99.59		GCR_RAT (21-597): 1.41e-91: 301: 22.50
+	Hs
		368832 HS90A_HUMAN (1-724): 0: 1072: 85.25		ESR1_HUMAN (61-592): 2.41e-97: 311: 22.79
+	Hs
		431608 HS90A_HUMAN (1-724): 0: 1072: 85.25		PPARG_HUMAN (120-594): 8.32e-99: 311: 21.55
+	Hs
		432122 HS90A_HUMAN (1-724): 0: 1072: 85.25		ESR2_HUMAN (128-592): 7.55e-97: 307: 24.07
+	Hs
		377015 HS90A_HUMAN (1-724): 0: 1072: 85.25		GCR_HUMAN (21-597): 6.09e-93: 304: 22.09
+	Rn
		415141 HS90A_RAT (1-724): 0: 1070: 84.45		GCR_RAT (21-597): 1.41e-91: 301: 22.50
+	Hs
		538103 ENPL_HUMAN (3-693): 0: 917: 46.44		NR4A1_HUMAN (1-598): 8.52e-140: 420: 100.00
+	Hs
		368916 ENPL_HUMAN (3-693): 0: 917: 46.44		ESR1_HUMAN (61-592): 2.41e-97: 311: 22.79
+	Hs
		377062 ENPL_HUMAN (3-693): 0: 917: 46.44		GCR_HUMAN (21-597): 6.09e-93: 304: 22.09