HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: LG3BP (Q08380)
Galectin-3-binding protein (Basement membrane autoantigen p105) (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (MAC2BP) (Mac-2 BP) (Tumor-associated antigen 90K)
Gene: LGALS3BP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	23443559, 22939624
Identification Methods	affinity chromatography technology, luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 585
+	Hs
		431780 HS90A_HUMAN (1-724): 0: 1072: 85.25		LG3BP_HUMAN (1-585): 0: 646: 100.00
+	Hs
		438402 HS90B_HUMAN (1-724): 0: 1086: 100.00		KLHL6_HUMAN (139-506): 2.49e-85: 279: 15.31
+	Hs
		438555 HS90B_HUMAN (1-724): 0: 1086: 100.00		KLHL1_HUMAN (93-506): 8.26e-83: 276: 14.91
+	Hs
		438582 HS90B_HUMAN (1-724): 0: 1086: 100.00		KLH13_HUMAN (104-516): 9.08e-83: 273: 15.86
+	Hs
		438163 HS90B_HUMAN (1-724): 0: 1086: 100.00		KEAP1_HUMAN (110-507): 3.23e-82: 271: 14.74
+	Hs
		432115 HS90A_HUMAN (1-724): 0: 1072: 85.25		KLHL6_HUMAN (139-506): 2.49e-85: 279: 15.31
+	Hs
		432290 HS90A_HUMAN (1-724): 0: 1072: 85.25		KLHL1_HUMAN (93-506): 8.26e-83: 276: 14.91
+	Hs
		438426 HS90B_HUMAN (1-724): 0: 1086: 100.00		KLH29_HUMAN (110-506): 7.03e-76: 260: 15.02
+	Hs
		432323 HS90A_HUMAN (1-724): 0: 1072: 85.25		KLH13_HUMAN (104-516): 9.08e-83: 273: 15.86
+	Hs
		438266 HS90B_HUMAN (1-724): 0: 1086: 100.00		KLH10_HUMAN (116-509): 3.35e-77: 258: 13.50
+	Hs
		431841 HS90A_HUMAN (1-724): 0: 1072: 85.25		KEAP1_HUMAN (110-507): 3.23e-82: 271: 14.74
+	Hs
		438236 HS90B_HUMAN (1-724): 0: 1086: 100.00		KLH26_HUMAN (128-436): 3.37e-76: 255: 16.29
+	Hs
		432143 HS90A_HUMAN (1-724): 0: 1072: 85.25		KLH29_HUMAN (110-506): 7.03e-76: 260: 15.02
+	Hs
		431957 HS90A_HUMAN (1-724): 0: 1072: 85.25		KLH10_HUMAN (116-509): 3.35e-77: 258: 13.50
+	Hs
		431925 HS90A_HUMAN (1-724): 0: 1072: 85.25		KLH26_HUMAN (128-436): 3.37e-76: 255: 16.29
+	Hs
		432394 HS90A_HUMAN (1-724): 0: 1072: 85.25		LOXL2_HUMAN (24-125): 1.86e-18: 91.3: 34.82
+	Hs
		538455 ENPL_HUMAN (3-693): 0: 917: 46.44		LOXL2_HUMAN (24-125): 1.86e-18: 91.3: 34.82
+	Hs
		1162529 Q6PK50_HUMAN (1-350): 0: 618: 99.71		KLHL1_HUMAN (93-506): 8.26e-83: 276: 14.91