Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: TEBP (Q15185)
Prostaglandin E synthase 3 (EC 5.3.99.3) (Cytosolic prostaglandin E2 synthase) (cPGES) (Hsp90 co-chaperone) (Progesterone receptor complex p23) (Telomerase-binding protein p23)
Gene: PTGES3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.753

The method score is based on:

Property Details
Experiments 10543959, 17010336, 18285346, 33961781, 35271311, 21183720, 21988832, 25036637
Identification Methods pull down, affinity chromatography technology, two hybrid, mass spectrometry studies of complexes, nuclear magnetic resonance, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006457 - protein folding
GO:0007004 - telomere maintenance via telomerase
and 7 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 724
Hs

1 160
+ Mm
+ Hs
+ Hs
+ Sc
+ Sc
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024