Interactor 1: SRPRA (P08240)
Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha)
Gene: SRPRA

Interactor 2: SRPRB (Q9Y5M8)
Signal recognition particle receptor subunit beta (SR-beta) (Protein APMCF1)
Gene: SRPRB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.932

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 26496610, 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SRP-alpha_N~SRPRB, SRP54~SRPRB
Common GO terms GO:0005525 - GTP binding
GO:0005785 - signal recognition particle receptor complex
GO:0005789 - endoplasmic reticulum membrane
GO:0006617 - SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
GO:0006886 - intracellular protein transport
and 2 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 638
Hs

1 271
+ Hs
+ Hs
+ Dm
+ Tt
+ Hs
+ Sc
+ Sc

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Last updated: 15 Jul 2024