Protein: ZA2G
Zinc-alpha-2-glycoprotein (Zn-alpha-2-GP) (Zn-alpha-2-glycoprotein)

Gene: ZA2G, AZGP1
Organism: Homo sapiens
Interactions: 173
UniProt ID: P25311

Gene Ontology (top 5):
GO:0001580 - detection of chemical stimulus involved in sensory perception of bitter taste
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0002476 - antigen processing and presentation of endogenous peptide antigen via MHC class Ib
GO:0002486 - antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
GO:0004540 - RNA nuclease activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

671787

MMRN1
Multimerin-1

1

1

High-throughput

0.691

High

671826

FNDC5
Fibronectin type III domain-containing protein 5

1

2

High-throughput

0.691

High

420243

IFNA4
Interferon alpha-4

1

0

High-throughput

0.656

High

671870

UBQL2
Ubiquilin-2

3

1

High-throughput

0.653

High

671782

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

2

3

High-throughput

0.628

High

671799

ZIC1
Zinc finger protein ZIC 1

2

1

High-throughput

0.628

High

369313

A1AT
Alpha-1-antitrypsin

1

1

High-throughput

0.618

High

455635

KLK3
Prostate-specific antigen

1

6

High-throughput

0.618

High

671756

SPB3
Serpin B3

1

2

High-throughput

0.618

High

671842

SPB12
Serpin B12

1

2

High-throughput

0.618

High

671868

PD1L1
Programmed cell death 1 ligand 1

1

17

High-throughput

0.618

High

671879

LOXL2
Lysyl oxidase homolog 2

1

1

High-throughput

0.618

High

671776

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

0

High-throughput

0.602

High

671857

DDX31
ATP-dependent DNA helicase DDX31

2

0

High-throughput

0.602

High

371195

MYC
Myc proto-oncogene protein

2

2

High-throughput

0.584

High

671796

TNIP1
TNFAIP3-interacting protein 1

3

5

High-throughput

0.578

High

379215

IGHG1
Immunoglobulin heavy constant gamma 1

1

4

High-throughput

0.575

High

671779

LG3BP
Galectin-3-binding protein

1

1

High-throughput

0.575

High

671804

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.575

High

671878

PRG3
Proteoglycan 3

1

6

High-throughput

0.575

High

671866

TB22B
TBC1 domain family member 22B

2

1

High-throughput

0.574

High

536527

HSP7C
Heat shock cognate 71 kDa protein

2

1

High-throughput

0.571

High

413219

P53
Cellular tumor antigen p53

2

0

Small-scale

0.559

High

671791

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

2

High-throughput

0.553

High

671832

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

2

High-throughput

0.553

High

671875

FND3A
Fibronectin type-III domain-containing protein 3A

1

1

High-throughput

0.553

High

671869

RHG23
Rho GTPase-activating protein 23

2

0

High-throughput

0.547

High

406961

THY1
Thy-1 membrane glycoprotein

1

0

High-throughput

0.546

High

626075

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

0

High-throughput

0.546

High

222353

TSN6
Tetraspanin-6

1

2

High-throughput

0.536

High

296873

RASF9
Ras association domain-containing protein 9

1

1

High-throughput

0.536

High

355430

NSD2
Histone-lysine N-methyltransferase NSD2

1

2

High-throughput

0.536

High

622755

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

1

High-throughput

0.536

High

625198

CSK22
Casein kinase II subunit alpha'

1

3

High-throughput

0.536

High

671758

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

1

1

High-throughput

0.536

High

671761

GLPK
Glycerol kinase

1

1

High-throughput

0.536

High

671762

CCR1
C-C chemokine receptor type 1

1

3

High-throughput

0.536

High

671765

PSB10
Proteasome subunit beta type-10

1

1

High-throughput

0.536

High

671768

PRKX
cAMP-dependent protein kinase catalytic subunit PRKX

1

1

High-throughput

0.536

High

671800

ZYX
Zyxin

1

2

High-throughput

0.536

High

671824

ASCC1
Activating signal cointegrator 1 complex subunit 1

1

2

High-throughput

0.536

High

671834

DNJC9
DnaJ homolog subfamily C member 9

1

8

High-throughput

0.536

High

671850

CDK19
Cyclin-dependent kinase 19

1

6

High-throughput

0.536

High

671830

ARH40
Rho guanine nucleotide exchange factor 40

2

1

High-throughput

0.521

High

168191

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.513

High

292556

RENR
Renin receptor

1

0

High-throughput

0.513

High

331633

MBD4
Methyl-CpG-binding domain protein 4

1

0

High-throughput

0.513

High

351660

SG1D1
Secretoglobin family 1D member 1

1

0

High-throughput

0.513

High

352682

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

0

High-throughput

0.513

High

391569

FRIH
Ferritin heavy chain

1

0

High-throughput

0.513

High

666797

CCNC
Cyclin-C

1

0

High-throughput

0.513

High

671771

DSCR6
Protein ripply3

1

0

High-throughput

0.513

High

671778

GABPA
GA-binding protein alpha chain

1

0

High-throughput

0.513

High

671786

ZN154
Zinc finger protein 154

1

0

High-throughput

0.513

High

671811

AMTN
Amelotin

1

0

High-throughput

0.513

High

671815

DET1
DET1 homolog

1

0

High-throughput

0.513

High

671816

ZN550
Zinc finger protein 550

1

0

High-throughput

0.513

High

671831

ITLN2
Intelectin-2

1

0

High-throughput

0.513

High

671846

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.513

High

671856

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

0

High-throughput

0.513

High

671858

COE2
Transcription factor COE2

1

0

High-throughput

0.513

High

671873

PHF8
Histone lysine demethylase PHF8

1

0

High-throughput

0.513

High

578382

BRAF
Serine/threonine-protein kinase B-raf

1

2

High-throughput

0.506

High

66482

RASFA
Ras association domain-containing protein 10

1

1

High-throughput

0.489

High

335229

CXB5
Gap junction beta-5 protein

1

3

High-throughput

0.489

High

671847

SH23A
SH2 domain-containing protein 3A

1

6

High-throughput

0.489

High

671860

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

6

High-throughput

0.489

High

671865

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.489

High

671867

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

1

3

High-throughput

0.489

High

671877

TDRKH
Tudor and KH domain-containing protein

1

4

High-throughput

0.489

High

407790

SHBG
Sex hormone-binding globulin

1

5

Small-scale

0.481

High

671763

MRP1
Multidrug resistance-associated protein 1

1

1

High-throughput

0.481

High

404677

PRIO
Major prion protein

1

0

Small-scale

0.479

High

315135

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

407836

SEMG1
Semenogelin-1

1

1

High-throughput

0.479

High

424138

S10A8
Protein S100-A8

1

1

High-throughput

0.479

High

456615

ANXA2
Annexin A2

1

1

High-throughput

0.479

High

563221

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.479

High

582545

PPAP
Prostatic acid phosphatase

1

1

High-throughput

0.479

High

667531

CDK2
Cyclin-dependent kinase 2

1

3

High-throughput

0.479

High

671757

PML
Protein PML

1

3

High-throughput

0.479

High

671764

MCM5
DNA replication licensing factor MCM5

1

3

High-throughput

0.479

High

671767

MCM2
DNA replication licensing factor MCM2

1

5

High-throughput

0.479

High

671774

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.479

High

671777

SEMG2
Semenogelin-2

1

1

High-throughput

0.479

High

671780

DSC1
Desmocollin-1

1

4

High-throughput

0.479

High

671788

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

671797

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

671798

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.479

High

671835

TOPB1
DNA topoisomerase 2-binding protein 1

1

1

High-throughput

0.479

High

671836

RBP56
TATA-binding protein-associated factor 2N

1

1

High-throughput

0.479

High

671851

FACD2
Fanconi anemia group D2 protein

1

6

High-throughput

0.479

High

671852

ACE2
Angiotensin-converting enzyme 2

1

2

High-throughput

0.479

High

671854

GTPB4
GTP-binding protein 4

1

1

High-throughput

0.479

High

671874

SMC3
Structural maintenance of chromosomes protein 3

1

3

High-throughput

0.479

High

302380

RNF8
E3 ubiquitin-protein ligase RNF8

1

0

High-throughput

0.458

High

389647

A1AG1
Alpha-1-acid glycoprotein 1

1

0

High-throughput

0.458

High

391125

HEMO
Hemopexin

1

0

High-throughput

0.458

High

391726

STAT
Statherin

1

0

High-throughput

0.458

High

423608

ARGI1
Arginase-1

1

0

High-throughput

0.458

High

465835

MSMB
Beta-microseminoprotein

1

0

High-throughput

0.458

High

590806

TIMP2
Metalloproteinase inhibitor 2

1

0

High-throughput

0.458

High

671759

LCN1
Lipocalin-1

1

0

High-throughput

0.458

High

671760

CASPE
Caspase-14

1

0

High-throughput

0.458

High

671766

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

671775

1433Z
14-3-3 protein zeta/delta

1

0

Small-scale

0.458

High

671781

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.458

High

671789

DX39B
Spliceosome RNA helicase DDX39B

1

0

High-throughput

0.458

High

671794

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

High-throughput

0.458

High

671801

PROL4
Proline-rich protein 4

1

0

High-throughput

0.458

High

671805

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.458

High

671807

NIPBL
Nipped-B-like protein

1

0

High-throughput

0.458

High

671808

TET2
Methylcytosine dioxygenase TET2

1

0

Small-scale

0.458

High

671859

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

671783

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

4

High-throughput

0.445

High

671784

STK4
Serine/threonine-protein kinase 4

1

3

High-throughput

0.445

High

671790

DAG1
Dystroglycan 1

1

1

Small-scale

0.445

High

671821

SULF2
Extracellular sulfatase Sulf-2

1

2

High-throughput

0.445

High

671837

WNT2B
Protein Wnt-2b

1

2

Small-scale

0.445

High

671844

CK5P2
CDK5 regulatory subunit-associated protein 2

1

1

High-throughput

0.445

High

293222

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.437

High

671795

CUL7
Cullin-7

1

4

High-throughput

0.437

High

671813

SYDE1
Rho GTPase-activating protein SYDE1

1

1

High-throughput

0.437

High

671819

ZCH18
Zinc finger CCCH domain-containing protein 18

1

1

High-throughput

0.437

High

671839

SEH1
Nucleoporin SEH1

1

3

High-throughput

0.437

High

671863

ANLN
Anillin

1

1

High-throughput

0.437

High

671876

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

1

Small-scale

0.437

High

671769

T2AG
Transcription initiation factor IIA subunit 2

1

0

High-throughput

0.426

High

671793

RFTN1
Raftlin

1

0

High-throughput

0.426

High

671828

INADL
InaD-like protein

1

0

High-throughput

0.426

High

671845

MYCBP
c-Myc-binding protein

1

0

High-throughput

0.426

High

671849

RSRP1
Arginine/serine-rich protein 1

1

0

High-throughput

0.426

High

284542

ECI2
Enoyl-CoA delta isomerase 2

1

3

High-throughput

0.407

High

671772

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

2

High-throughput

0.407

High

671785

IFT88
Intraflagellar transport protein 88 homolog

1

1

High-throughput

0.407

High

671792

GLPK3
Glycerol kinase 3

1

1

High-throughput

0.407

High

671823

PI4P1
Putative inactive phosphatidylinositol 4-kinase alpha-like protein P1

1

3

High-throughput

0.407

High

671840

MRAP2
Melanocortin-2 receptor accessory protein 2

1

1

High-throughput

0.407

High

671841

CEP63
Centrosomal protein of 63 kDa

1

1

High-throughput

0.407

High

671864

PDLI7
PDZ and LIM domain protein 7

1

3

High-throughput

0.407

High

671871

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

2

High-throughput

0.407

High

671848

PHAF1
Phagosome assembly factor 1

2

0

High-throughput

0.328

High

185161

FANCG
Fanconi anemia group G protein

1

0

High-throughput

0.279

Low

671770

STX17
Syntaxin-17

1

0

High-throughput

0.279

Low

671773

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

0

High-throughput

0.279

Low

671802

T176B
Transmembrane protein 176B

1

0

High-throughput

0.279

Low

671803

VWA3B
von Willebrand factor A domain-containing protein 3B

1

0

High-throughput

0.279

Low

671814

UBP53
Ubiquitin carboxyl-terminal hydrolase 53

1

0

High-throughput

0.279

Low

671820

AROS
Active regulator of SIRT1

1

0

High-throughput

0.279

Low

671827

AT11C
Phospholipid-transporting ATPase IG

1

0

High-throughput

0.279

Low

671829

MYBPP
MYCBP-associated protein

1

0

High-throughput

0.279

Low

671838

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

671843

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.279

Low

671862

TSSP
Thymus-specific serine protease

1

0

High-throughput

0.279

Low

671872

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

0

High-throughput

0.279

Low

671853

NUF2
Kinetochore protein Nuf2

1

0

High-throughput

0.251

Low

360712

COX3
Cytochrome c oxidase subunit 3

1

0

Small-scale

0.249

Low

649759

SPR2E
Small proline-rich protein 2E

1

0

High-throughput

0.249

Low

659130

LORI
Loricrin

1

0

High-throughput

0.249

Low

671806

KPLCE
Protein KPLCE

1

0

High-throughput

0.249

Low

671810

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.249

Low

671817

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.249

Low

671818

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.249

Low

671822

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.249

Low

671855

DDX24
ATP-dependent RNA helicase DDX24

1

0

High-throughput

0.249

Low

671861

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.249

Low

927

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

219601

B2L11
Bcl-2-like protein 11

1

0

High-throughput

0.232

Low

261087

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low

671809

CNKR3
Connector enhancer of kinase suppressor of ras 3

1

0

High-throughput

0.232

Low

671812

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

0

High-throughput

0.232

Low

671825

POC5
Centrosomal protein POC5

1

0

Small-scale

0.232

Low

671833

JPH3
Junctophilin-3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025