Protein: EF1B
Elongation factor 1-beta (EF-1-beta)

Gene: EF1B, EEF1B2
Organism: Homo sapiens
Interactions: 186
UniProt ID: P24534

Gene Ontology (top 5):
GO:0003746 - translation elongation factor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005853 - eukaryotic translation elongation factor 1 complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

623069

EF1D
Elongation factor 1-delta

4

2

High-throughput

0.895

High

623101

EF1A1
Elongation factor 1-alpha 1

4

5

High-throughput

0.895

High

623107

EF1A2
Elongation factor 1-alpha 2

3

5

High-throughput

0.867

High

623067

EF1G
Elongation factor 1-gamma

11

16

High-throughput

0.761

High

623082

HD
Huntingtin

2

1

High-throughput

0.621

High

623123

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.618

High

623116

CUL3
Cullin-3

2

8

High-throughput

0.611

High

475347

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

1

Small-scale

0.584

High

623080

CCNF
Cyclin-F

2

1

High-throughput

0.584

High

623108

EP300
Histone acetyltransferase p300

2

2

High-throughput

0.584

High

623178

ANLN
Anillin

2

1

High-throughput

0.584

High

623064

EF1B
Elongation factor 1-beta

1

2

Small-scale

0.575

High

623095

AF17
Protein AF-17

2

4

High-throughput

0.574

High

369002

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

411600

LCK
Tyrosine-protein kinase Lck

2

1

High-throughput

0.571

High

623118

PTK6
Protein-tyrosine kinase 6

2

1

High-throughput

0.571

High

623102

CSK21
Casein kinase II subunit alpha

1

3

High-throughput

0.569

High

623153

SPRY4
SPRY domain-containing protein 4

2

1

High-throughput

0.553

High

532389

TCTP
Translationally-controlled tumor protein

1

3

Small-scale

0.550

High

581433

VCAM1
Vascular cell adhesion protein 1

2

1

High-throughput

0.549

High

517870

HARS1
Histidine--tRNA ligase, cytoplasmic

1

0

Small-scale

0.537

High

128447

DNM1L
Dynamin-1-like protein

1

1

High-throughput

0.536

High

336364

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.536

High

496325

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.536

High

528567

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

537599

NCF1
Neutrophil cytosol factor 1

1

1

High-throughput

0.536

High

623071

COR1A
Coronin-1A

1

5

High-throughput

0.536

High

623072

CNR2
Cannabinoid receptor 2

1

2

Small-scale

0.536

High

623074

BMI1
Polycomb complex protein BMI-1

1

5

High-throughput

0.536

High

623092

NEK4
Serine/threonine-protein kinase Nek4

1

3

High-throughput

0.536

High

623114

CUL1
Cullin-1

1

8

High-throughput

0.536

High

623115

CUL2
Cullin-2

1

8

High-throughput

0.536

High

623127

BOREA
Borealin

1

1

High-throughput

0.536

High

623158

CUL5
Cullin-5

1

8

High-throughput

0.536

High

623167

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

High-throughput

0.536

High

623179

BATF3
Basic leucine zipper transcriptional factor ATF-like 3

1

10

High-throughput

0.536

High

157008

AIM2
Interferon-inducible protein AIM2

1

0

High-throughput

0.513

High

623078

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.513

High

623084

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

623140

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.513

High

623148

RIN3
Ras and Rab interactor 3

1

0

High-throughput

0.513

High

394139

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

623079

VHL
von Hippel-Lindau disease tumor suppressor

1

1

Small-scale

0.501

High

623157

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

2

High-throughput

0.501

High

362824

FINC
Fibronectin

1

1

High-throughput

0.489

High

452629

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

579171

ATF3
Cyclic AMP-dependent transcription factor ATF-3

1

10

High-throughput

0.489

High

623088

CEBPD
CCAAT/enhancer-binding protein delta

1

9

High-throughput

0.489

High

623164

ERP27
Endoplasmic reticulum resident protein 27

1

2

High-throughput

0.489

High

623174

KDM4C
Lysine-specific demethylase 4C

1

3

High-throughput

0.489

High

623161

WBP2
WW domain-binding protein 2

1

0

Small-scale

0.480

High

119177

LEG9
Galectin-9

1

1

High-throughput

0.479

High

148408

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.479

High

261081

SH3L1
Adapter SH3BGRL

1

1

Small-scale

0.479

High

267894

EED
Polycomb protein EED

1

6

High-throughput

0.479

High

282531

RNF8
E3 ubiquitin-protein ligase RNF8

1

3

High-throughput

0.479

High

294379

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

302915

HEXI1
Protein HEXIM1

1

1

High-throughput

0.479

High

312482

ARI2
E3 ubiquitin-protein ligase ARIH2

1

1

High-throughput

0.479

High

326443

SNAI1
Zinc finger protein SNAI1

1

1

High-throughput

0.479

High

345950

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

417944

NPM
Nucleophosmin

1

1

High-throughput

0.479

High

501696

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.479

High

503457

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

569201

CEBPB
CCAAT/enhancer-binding protein beta

1

9

High-throughput

0.479

High

617428

CRCM
Colorectal mutant cancer protein

1

2

High-throughput

0.479

High

623073

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

1

High-throughput

0.479

High

623077

BRCA1
Breast cancer type 1 susceptibility protein

1

2

High-throughput

0.479

High

623083

YAP1
Transcriptional coactivator YAP1

1

6

High-throughput

0.479

High

623089

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

623090

CDK7
Cyclin-dependent kinase 7

1

3

High-throughput

0.479

High

623093

ATX3
Ataxin-3

1

1

High-throughput

0.479

High

623094

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.479

High

623097

UBC12
NEDD8-conjugating enzyme Ubc12

1

4

High-throughput

0.479

High

623099

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

623100

1433Z
14-3-3 protein zeta/delta

1

3

High-throughput

0.479

High

623103

RED1
Double-stranded RNA-specific editase 1

1

2

High-throughput

0.479

High

623105

EWS
RNA-binding protein EWS

1

1

High-throughput

0.479

High

623106

KPCZ
Protein kinase C zeta type

1

2

High-throughput

0.479

High

623109

FOXO1
Forkhead box protein O1

1

4

High-throughput

0.479

High

623113

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

623117

DX39B
Spliceosome RNA helicase DDX39B

1

1

Small-scale

0.479

High

623119

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

4

High-throughput

0.479

High

623120

IF4A2
Eukaryotic initiation factor 4A-II

1

1

High-throughput

0.479

High

623122

CUL7
Cullin-7

1

1

High-throughput

0.479

High

623126

LARP7
La-related protein 7

1

1

High-throughput

0.479

High

623129

TET5C
Terminal nucleotidyltransferase 5C

1

1

High-throughput

0.479

High

623130

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

623133

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

623136

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

7

High-throughput

0.479

High

623137

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

1

High-throughput

0.479

High

623141

GOLI
E3 ubiquitin-protein ligase RNF130

1

1

High-throughput

0.479

High

623143

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

623145

RPTOR
Regulatory-associated protein of mTOR

1

4

High-throughput

0.479

High

623146

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.479

High

623147

TNIP2
TNFAIP3-interacting protein 2

1

1

High-throughput

0.479

High

623150

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

623152

NUDC2
NudC domain-containing protein 2

1

1

High-throughput

0.479

High

623154

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

623159

FBXW7
F-box/WD repeat-containing protein 7

1

3

High-throughput

0.479

High

623162

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

623163

OPTN
Optineurin

1

3

High-throughput

0.479

High

623166

NECD
Necdin

1

1

High-throughput

0.479

High

623169

ARP6
Actin-related protein 6

1

1

High-throughput

0.479

High

623171

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

7

Small-scale

0.479

High

623176

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

7

High-throughput

0.479

High

623177

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

623180

FBX6
F-box only protein 6

1

1

High-throughput

0.479

High

623181

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.479

High

623184

HDAC6
Histone deacetylase 6

1

2

Small-scale

0.479

High

623185

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

623187

FZR1
Fizzy-related protein homolog

1

4

High-throughput

0.479

High

623188

FAF1
FAS-associated factor 1

1

1

High-throughput

0.479

High

241973

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

298163

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

337949

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

351259

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.458

High

505552

EPB41
Protein 4.1

1

0

High-throughput

0.458

High

610229

CBL
E3 ubiquitin-protein ligase CBL

1

0

High-throughput

0.458

High

623065

PSA3
Proteasome subunit alpha type-3

1

0

Small-scale

0.458

High

623075

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

623085

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

623110

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.458

High

623131

SCND3
SCAN domain-containing protein 3

1

0

High-throughput

0.458

High

623138

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

623151

CEMIP
Cell migration-inducing and hyaluronan-binding protein

1

0

Small-scale

0.458

High

623165

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

623173

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

623182

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

Small-scale

0.458

High

623144

ULK2
Serine/threonine-protein kinase ULK2

1

2

High-throughput

0.457

High

173840

MK13
Mitogen-activated protein kinase 13

1

4

Small-scale

0.445

High

305969

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

4

High-throughput

0.445

High

373695

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.445

High

623066

SYVC
Valine--tRNA ligase

1

6

Small-scale

0.445

High

623096

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

4

High-throughput

0.445

High

623125

CRY1
Cryptochrome-1

1

1

Small-scale

0.445

High

623128

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

623170

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

4

High-throughput

0.445

High

623172

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

4

High-throughput

0.445

High

623156

AP2C
Transcription factor AP-2 gamma

1

0

High-throughput

0.438

High

205058

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

239495

EIF1B
Eukaryotic translation initiation factor 1b

1

1

High-throughput

0.437

High

243944

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.437

High

329367

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

351714

SOMA
Somatotropin

1

1

High-throughput

0.437

High

354295

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

1

High-throughput

0.437

High

384284

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

428922

ADRB2
Beta-2 adrenergic receptor

1

1

High-throughput

0.437

High

473433

RBY1D
RNA-binding motif protein, Y chromosome, family 1 member D

1

1

High-throughput

0.437

High

530430

ITA4
Integrin alpha-4

1

1

High-throughput

0.437

High

551970

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

623068

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

623076

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

623086

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

623091

CDK9
Cyclin-dependent kinase 9

1

4

High-throughput

0.437

High

623098

WDR5
WD repeat-containing protein 5

1

3

High-throughput

0.437

High

623111

RFA4
Replication protein A 30 kDa subunit

1

2

High-throughput

0.437

High

623112

TIF1B
Transcription intermediary factor 1-beta

1

3

High-throughput

0.437

High

623121

RBM39
RNA-binding protein 39

1

1

High-throughput

0.437

High

623124

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.437

High

623134

ASXL2
Putative Polycomb group protein ASXL2

1

4

High-throughput

0.437

High

623135

MEPCE
7SK snRNA methylphosphate capping enzyme

1

1

High-throughput

0.437

High

623142

ASXL1
Polycomb group protein ASXL1

1

3

High-throughput

0.437

High

623149

TIP
T-cell immunomodulatory protein

1

1

High-throughput

0.437

High

623155

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

623160

IGSF8
Immunoglobulin superfamily member 8

1

1

High-throughput

0.437

High

623168

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

623186

BAZ1B
Tyrosine-protein kinase BAZ1B

1

4

High-throughput

0.437

High

623189

SRRM2
Serine/arginine repetitive matrix protein 2

1

3

High-throughput

0.437

High

623190

AAR2
Protein AAR2 homolog

1

1

High-throughput

0.437

High

623104

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.426

High

401435

JUN
Transcription factor Jun

1

6

High-throughput

0.407

High

623081

CNDD3
Condensin-2 complex subunit D3

1

1

High-throughput

0.407

High

623087

CEBPA
CCAAT/enhancer-binding protein alpha

1

7

High-throughput

0.373

High

295937

MTA2
Metastasis-associated protein MTA2

2

0

High-throughput

0.298

High

344792

TIMP1
Metalloproteinase inhibitor 1

1

0

High-throughput

0.282

High

555297

H2AX
Histone H2AX

1

0

High-throughput

0.279

Low

623070

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.279

Low

353261

CD4
T-cell surface glycoprotein CD4

1

0

Small-scale

0.249

Low

560376

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

0

Small-scale

0.249

Low

623139

MGDP1
Magnesium-dependent phosphatase 1

1

0

High-throughput

0.249

Low

623175

HES4
Transcription factor HES-4

1

0

High-throughput

0.249

Low

623183

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.249

Low

926

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

623132

SHLD3
Shieldin complex subunit 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024