Interactor 1: MMP3 (P08254)
Stromelysin-1 (SL-1) (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1)
Gene: MMP3

Interactor 2: MMP10 (P09238)
Stromelysin-2 (SL-2) (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2)
Gene: MMP10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Hemopexin~Hemopexin, Hemopexin~Peptidase_M10, Hemopexin~PG_binding_1, Peptidase_M10~Peptidase_M10, PG_binding_1~Peptidase_M10, PG_binding_1~PG_binding_1
Common GO terms GO:0004222 - metalloendopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006508 - proteolysis
and 5 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 477
Hs

1 476
+ Hs
+ Hs
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024