Protein: RV161
Reduced viability upon starvation protein 161

Gene: RV161, RVS161
Organism: Saccharomyces cerevisiae S288C
Interactions: 140
UniProt ID: P25343

Gene Ontology (top 5):
GO:0000747 - conjugation with cellular fusion
GO:0005829 - cytosol
GO:0005937 - mating projection
GO:0006897 - endocytosis
GO:0006970 - response to osmotic stress

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

672313

RV167
Reduced viability upon starvation protein 167

22

18

Small-scale

0.991

High

672365

GYP5
GTPase-activating protein GYP5

7

4

Small-scale

0.740

High

672349

FUS2
Nuclear fusion protein FUS2

7

0

Small-scale

0.709

High

672303

AIM3
Altered inheritance of mitochondria protein 3

4

4

Small-scale

0.693

High

672345

GYL1
Probable GTPase-activating protein GYL1

6

3

Small-scale

0.664

High

672366

LAS17
Proline-rich protein LAS17

3

10

Small-scale

0.648

High

523156

HSP71
Heat shock protein SSA1

3

5

High-throughput

0.643

High

672321

SSB2
Ribosome-associated molecular chaperone SSB2

2

3

High-throughput

0.601

High

672315

RSP5
E3 ubiquitin-protein ligase RSP5

2

5

High-throughput

0.600

High

578910

HSC82
ATP-dependent molecular chaperone HSC82

2

4

High-throughput

0.584

High

672323

GVP36
Protein GVP36

1

1

Small-scale

0.552

High

672305

ARPC1
Actin-related protein 2/3 complex subunit 1

1

2

High-throughput

0.541

High

672287

MKK2
MAP kinase kinase MKK2/SSP33

1

4

High-throughput

0.536

High

672296

SPT7
SAGA complex subunit SPT7

1

2

High-throughput

0.536

High

672364

HSP42
Heat shock protein 42

2

1

High-throughput

0.533

High

672362

RUD3
GRIP domain-containing protein RUD3

2

2

Small-scale

0.533

High

597963

NCPR
NADPH--cytochrome P450 reductase

1

2

High-throughput

0.515

High

672213

CDC10
Cell division control protein 10

1

1

High-throughput

0.515

High

672280

YCT3
Uncharacterized protein YCR043C

1

1

High-throughput

0.515

High

672290

RAD23
UV excision repair protein RAD23

1

3

High-throughput

0.515

High

672352

CORO
Coronin-like protein

1

1

High-throughput

0.515

High

672370

DPH3
Diphthamide biosynthesis protein 3

1

1

High-throughput

0.515

High

672302

RXT2
Transcriptional regulatory protein RXT2

1

0

High-throughput

0.513

High

672340

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.513

High

154139

RL36B
Large ribosomal subunit protein eL36B

1

1

Small-scale

0.508

High

672335

APP1
Phosphatidate phosphatase APP1

1

1

Small-scale

0.508

High

672342

SXM1
Importin beta SMX1

1

1

Small-scale

0.508

High

358973

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.500

High

359431

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

1

High-throughput

0.500

High

405039

LEU3
3-isopropylmalate dehydrogenase

1

3

High-throughput

0.500

High

408292

GAL1
Galactokinase

1

1

High-throughput

0.500

High

439258

PDC1
Pyruvate decarboxylase isozyme 1

1

2

High-throughput

0.500

High

454079

DHE4
NADP-specific glutamate dehydrogenase 1

1

3

High-throughput

0.500

High

555016

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.500

High

592039

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.500

High

672289

HSP79
Heat shock protein homolog SSE2

1

9

High-throughput

0.500

High

672316

SAHH
Adenosylhomocysteinase

1

1

High-throughput

0.500

High

672327

CYP7
Peptidyl-prolyl cis-trans isomerase CYP7

1

0

High-throughput

0.493

High

672332

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.493

High

672285

XPO1
Exportin-1

1

2

High-throughput

0.489

High

672300

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

2

High-throughput

0.489

High

672331

YBP2
YAP1-binding protein 2

1

1

High-throughput

0.489

High

672311

DHE5
NADP-specific glutamate dehydrogenase 2

1

3

Small-scale

0.481

High

672359

ENG2
Glucan endo-1,3-beta-D-glucosidase 2

1

1

Small-scale

0.481

High

672363

PKH2
Serine/threonine-protein kinase PKH2

1

3

High-throughput

0.481

High

367702

ENO1
Enolase 1

1

0

High-throughput

0.479

High

408556

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

0

High-throughput

0.479

High

622322

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.479

High

672355

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.479

High

392286

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.479

High

433467

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.479

High

434854

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

435792

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

441725

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

502869

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.479

High

509416

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

8

High-throughput

0.479

High

509874

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

3

High-throughput

0.479

High

514474

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

670375

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

672281

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

672282

CDC48
Cell division control protein 48

1

3

High-throughput

0.479

High

672286

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

672291

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.479

High

672294

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.479

High

672299

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

672310

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

672326

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

672328

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

672338

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

672356

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.479

High

672361

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

656932

BUR1
Serine/threonine-protein kinase BUR1

1

3

High-throughput

0.470

High

671934

HAL4
Serine/threonine-protein kinase HAL4/SAT4

1

3

High-throughput

0.470

High

672312

SAW1
Single-strand annealing weakened protein 1

1

1

High-throughput

0.470

High

672319

SLX8
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8

1

1

High-throughput

0.470

High

672343

RAD33
DNA repair protein RAD33

1

1

High-throughput

0.470

High

672350

COA4
Cytochrome oxidase assembly factor 4

1

1

High-throughput

0.470

High

672368

YO098
Uncharacterized protein YOL098C

1

1

High-throughput

0.470

High

149605

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

454898

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

512277

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

672301

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

672307

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

672344

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.458

High

542945

CDC24
Cell division control protein 24

1

3

Small-scale

0.457

High

456339

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

2

High-throughput

0.457

High

590543

HSP26
Heat shock protein 26

1

1

High-throughput

0.457

High

603413

VATA
V-type proton ATPase catalytic subunit A

1

6

High-throughput

0.457

High

672318

IMB4
Importin subunit beta-4

1

2

High-throughput

0.457

High

453440

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.445

High

526003

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.445

High

543923

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

672288

HSP7F
Heat shock protein homolog SSE1

1

9

High-throughput

0.445

High

419366

H2A1
Histone H2A.1

1

1

High-throughput

0.437

High

419616

H2A2
Histone H2A.2

1

1

High-throughput

0.437

High

594213

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.437

High

672283

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

672284

BMH1
Protein BMH1

1

2

High-throughput

0.437

High

672297

SPT10
Protein SPT10

1

1

High-throughput

0.437

High

672298

SPT21
Protein SPT21

1

1

High-throughput

0.437

High

672320

YEY6
MYG1 protein YER156C

1

1

Small-scale

0.437

High

672333

GIS2
Zinc finger protein GIS2

1

2

High-throughput

0.437

High

672336

H3
Histone H3

1

1

High-throughput

0.437

High

672337

CDC14
Tyrosine-protein phosphatase CDC14

1

2

High-throughput

0.437

High

672339

ESP1
Separin

1

1

High-throughput

0.437

High

672341

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.437

High

672346

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

1

High-throughput

0.437

High

672351

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.437

High

672354

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.437

High

672367

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.437

High

672369

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.437

High

510229

HSP77
Import motor subunit, mitochondrial

1

4

High-throughput

0.407

High

671577

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.407

High

672317

HSP7E
Heat shock protein SSC3, mitochondrial

1

4

High-throughput

0.407

High

672334

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

High-throughput

0.407

High

417034

VDAC1
Non-selective voltage-gated ion channel 1

1

0

High-throughput

0.279

Low

533400

MITF2
Mitochondrial translation factor 2

1

0

High-throughput

0.279

Low

672295

PP2C3
Protein phosphatase 2C homolog 3

1

0

High-throughput

0.279

Low

672306

GRPE
GrpE protein homolog, mitochondrial

1

0

High-throughput

0.279

Low

672324

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.279

Low

672347

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.269

Low

672358

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.269

Low

672360

FCY1
Cytosine deaminase

1

0

High-throughput

0.269

Low

575393

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.261

Low

672322

MPM1
Mitochondrial peculiar membrane protein 1

1

0

High-throughput

0.261

Low

672293

TYE7
Transcription factor TYE7

1

0

High-throughput

0.251

Low

381896

H4
Histone H4

1

0

High-throughput

0.249

Low

401903

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.249

Low

647017

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

672292

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

672304

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

672314

EXO1
Exodeoxyribonuclease 1

1

0

High-throughput

0.249

Low

672353

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

672308

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.232

Low

672309

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.232

Low

672325

EMW1
Essential for maintenance of the cell wall protein 1

1

0

High-throughput

0.232

Low

672329

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.232

Low

672330

SPT20
SAGA complex subunit SPT20

1

0

High-throughput

0.232

Low

672348

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.232

Low

672357

HFI1
SAGA complex subunit HFI1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025