HitPredict

Interactor 1: GSTA1 (P08263)
Glutathione S-transferase A1 (EC 2.5.1.18) (13-hydroperoxyoctadecadienoate peroxidase) (EC 1.11.1.-) (Androst-5-ene-3,17-dione isomerase) (EC 5.3.3.-) (GST HA subunit 1) (GST class-alpha member 1) (GST-epsilon) (GSTA1-1) (GTH1) [Cleaved into: Glutathione S-transferase A1, N-terminally processed]
Gene: GSTA1

Interactor 2: GSTA3 (Q16772)
Glutathione S-transferase A3 (EC 2.5.1.18) (GST class-alpha member 3) (Glutathione S-transferase A3-3)
Gene: GSTA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GST_C~GST_C, GST_C~GST_N, GST_N~GST_N
Common GO terms	GO:0004364 - glutathione transferase activity GO:0005829 - cytosol GO:0006749 - glutathione metabolic process GO:0006805 - xenobiotic metabolic process GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 222 Hs			1 222
+	Hs
		439277 GSTA1_HUMAN (1-222): 2.01e-69: 213: 100.00		GSTA1_HUMAN (1-222): 4.16e-68: 210: 90.54
+	Hs
		448266 GSTA3_HUMAN (1-222): 2.89e-70: 215: 90.54		GSTA2_HUMAN (1-222): 3.48e-67: 207: 88.74
+	Hs
		439278 GSTA1_HUMAN (1-222): 2.01e-69: 213: 100.00		GSTA2_HUMAN (1-222): 3.48e-67: 207: 88.74
+	Hs
		439289 GSTA1_HUMAN (1-222): 2.01e-69: 213: 100.00		GSTA5_HUMAN (1-222): 1.56e-65: 203: 85.59
+	Hs
		448268 GSTA2_HUMAN (1-222): 2.88e-68: 210: 95.05		GSTA5_HUMAN (1-222): 1.56e-65: 203: 85.59
+	Hs
		240490 HPGDS_HUMAN (5-205): 1.9e-68: 210: 25.12		HPGDS_HUMAN (5-205): 3.66e-63: 196: 25.12
+	Ce
		488050 GSTP1_CAEEL (6-210): 5.38e-62: 194: 26.57		P91505_CAEEL (6-210): 2.06e-69: 212: 30.44
+	Hs
		171871 GSTA1_HUMAN (1-222): 2.01e-69: 213: 100.00		GSTA4_HUMAN (1-221): 2.49e-59: 187: 53.39
+	Hs
		171872 GSTA2_HUMAN (1-222): 2.88e-68: 210: 95.05		GSTA4_HUMAN (1-221): 2.49e-59: 187: 53.39
+	Hs
		171874 GSTA5_HUMAN (1-222): 6.06e-66: 204: 90.09		GSTA4_HUMAN (1-221): 2.49e-59: 187: 53.39
+	Hs
		439287 GSTA1_HUMAN (1-222): 2.01e-69: 213: 100.00		Q5JW85_HUMAN (52-222): 3.99e-55: 175: 100.00
+	Hs
		448267 GSTA2_HUMAN (1-222): 2.88e-68: 210: 95.05		Q5JW85_HUMAN (52-222): 3.99e-55: 175: 100.00
+	Ce
		488051 GSTP1_CAEEL (6-210): 5.38e-62: 194: 26.57		GSTPA_CAEEL (3-210): 6.97e-56: 178: 26.92
+	Hs
		974239 Q6FGJ9_HUMAN (1-218): 2.14e-58: 185: 23.35		GSTM4_HUMAN (1-218): 2.43e-59: 187: 20.89
+	Hs
		803865 Q6FGJ9_HUMAN (1-218): 2.14e-58: 185: 23.35		GSTM5_HUMAN (4-218): 1.36e-56: 180: 19.37