Protein: ARP2
Actin-related protein 2 (Actin-like protein ARP2) (Actin-like protein 2)

Gene: ARP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 153
UniProt ID: P32381

Gene Ontology (top 5):
GO:0000001 - mitochondrion inheritance
GO:0003779 - actin binding
GO:0005524 - ATP binding
GO:0005885 - Arp2/3 protein complex
GO:0005938 - cell cortex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

736120

ARP3
Actin-related protein 3

17

19

Small-scale

0.986

High

736090

ARPC1
Actin-related protein 2/3 complex subunit 1

14

18

Small-scale

0.984

High

736137

ARPC3
Actin-related protein 2/3 complex subunit 3

13

7

Small-scale

0.981

High

736154

LAS17
Proline-rich protein LAS17

11

11

Small-scale

0.977

High

736110

ARPC5
Actin-related protein 2/3 complex subunit 5

11

8

Small-scale

0.974

High

736123

ARPC2
Actin-related protein 2/3 complex subunit 2

9

6

Small-scale

0.972

High

736076

ARPC4
Actin-related protein 2/3 complex subunit 4

9

6

Small-scale

0.969

High

736134

MYO5
Myosin-5

4

17

Small-scale

0.891

High

736126

ACT
Actin

4

17

Small-scale

0.888

High

736118

TCPQ
T-complex protein 1 subunit theta

3

20

High-throughput

0.865

High

736149

AIM7
Protein AIM7

3

20

Small-scale

0.857

High

736139

CORO
Coronin-like protein

3

12

Small-scale

0.855

High

736107

TCPE
T-complex protein 1 subunit epsilon

2

20

High-throughput

0.811

High

736113

BNI1
Protein BNI1

2

19

High-throughput

0.799

High

736086

VRP1
Verprolin

2

10

High-throughput

0.793

High

736133

RUVB1
RuvB-like protein 1

2

10

High-throughput

0.789

High

587292

ABP1
Actin-binding protein

2

20

Small-scale

0.768

High

736109

PRK1
Actin-regulating kinase PRK1

1

3

Small-scale

0.740

High

470113

SPS1
Sporulation-specific protein 1

1

9

High-throughput

0.691

High

617377

GBB
Guanine nucleotide-binding protein subunit beta

1

8

High-throughput

0.691

High

736068

MKK2
MAP kinase kinase MKK2/SSP33

1

12

High-throughput

0.691

High

736125

CBK1
Serine/threonine-protein kinase CBK1

1

6

High-throughput

0.691

High

736128

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

9

High-throughput

0.691

High

736083

MYO3
Myosin-3

1

20

Small-scale

0.665

High

626647

HSP60
Heat shock protein 60, mitochondrial

1

15

High-throughput

0.646

High

736069

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

2

7

Small-scale

0.624

High

736132

SKY1
Serine/threonine-protein kinase SKY1

1

12

Small-scale

0.621

High

627837

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

1

7

High-throughput

0.618

High

633451

PP11
Serine/threonine-protein phosphatase PP1-1

1

8

High-throughput

0.618

High

464574

PBS2
MAP kinase kinase PBS2

1

8

High-throughput

0.618

High

736067

HOG1
Mitogen-activated protein kinase HOG1

1

7

High-throughput

0.618

High

736097

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.618

High

679477

CDC48
Cell division control protein 48

2

7

High-throughput

0.594

High

726832

HS104
Heat shock protein 104

2

1

High-throughput

0.594

High

736077

PRS6A
26S proteasome regulatory subunit 6A

2

5

Small-scale

0.586

High

736148

ATG9
Autophagy-related protein 9

2

1

Small-scale

0.584

High

736155

CMR1
DNA damage-binding protein CMR1

1

9

High-throughput

0.553

High

736096

END3
Actin cytoskeleton-regulatory complex protein END3

2

5

Small-scale

0.543

High

639546

RIR3
Ribonucleoside-diphosphate reductase large chain 2

1

1

High-throughput

0.536

High

721354

MCM4
DNA replication licensing factor MCM4

1

8

High-throughput

0.536

High

736070

DUR1
Urea amidolyase [Includes: Urea carboxylase

1

2

High-throughput

0.536

High

736078

PRS6B
26S proteasome regulatory subunit 6B homolog

1

3

High-throughput

0.536

High

736088

MCM7
DNA replication licensing factor MCM7

1

6

High-throughput

0.536

High

736089

ATG12
Ubiquitin-like protein ATG12

1

1

High-throughput

0.536

High

736122

PRS10
26S proteasome subunit RPT4

1

10

High-throughput

0.536

High

430807

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

2

6

Small-scale

0.535

High

736116

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

10

High-throughput

0.533

High

736119

YJ12B
Transposon Ty1-JR2 Gag-Pol polyprotein

1

0

High-throughput

0.513

High

736152

SWM1
Anaphase-promoting complex subunit SWM1

1

0

High-throughput

0.513

High

736102

RSP5
E3 ubiquitin-protein ligase RSP5

1

6

High-throughput

0.501

High

366968

ATPB
ATP synthase subunit beta, mitochondrial

1

6

High-throughput

0.500

High

399353

CARB
Carbamoyl phosphate synthase arginine-specific large chain

1

1

High-throughput

0.500

High

416401

HXKA
Hexokinase-1

1

2

High-throughput

0.500

High

452856

ATPA
ATP synthase subunit alpha, mitochondrial

1

6

High-throughput

0.500

High

471386

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

1

High-throughput

0.500

High

538330

PYC1
Pyruvate carboxylase 1

1

2

High-throughput

0.500

High

544145

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.500

High

592089

VATB
V-type proton ATPase subunit B

1

6

High-throughput

0.500

High

597069

BIP
Endoplasmic reticulum chaperone BiP

1

6

High-throughput

0.500

High

598826

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

2

High-throughput

0.500

High

598980

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

2

High-throughput

0.500

High

675808

MAS5
Mitochondrial protein import protein MAS5

1

4

High-throughput

0.500

High

701670

URA7
CTP synthase 1

1

3

High-throughput

0.500

High

736081

MDJ1
DnaJ homolog 1, mitochondrial

1

5

High-throughput

0.500

High

736091

YHI0
Putative proline--tRNA ligase YHR020W

1

1

High-throughput

0.500

High

452721

ADR1
Regulatory protein ADR1

1

1

High-throughput

0.489

High

647722

RFA1
Replication factor A protein 1

1

5

High-throughput

0.489

High

726005

NTH1
Endonuclease III homolog 1

1

1

High-throughput

0.489

High

736080

SPT7
SAGA complex subunit SPT7

1

20

High-throughput

0.489

High

736108

MET18
DNA repair/transcription protein MET18/MMS19

1

1

High-throughput

0.489

High

736124

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.489

High

736129

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

High-throughput

0.489

High

736141

IMH1
Golgin IMH1

1

20

High-throughput

0.489

High

736143

SHS1
Seventh homolog of septin 1

1

5

High-throughput

0.489

High

736147

RPN8
26S proteasome regulatory subunit RPN8

1

7

High-throughput

0.489

High

736151

PST2
Protoplast secreted protein 2

1

1

High-throughput

0.489

High

420897

PMA1
Plasma membrane ATPase 1

1

0

High-throughput

0.479

High

392404

HSP82
ATP-dependent molecular chaperone HSP82

1

6

High-throughput

0.479

High

579031

HSC82
ATP-dependent molecular chaperone HSC82

1

6

High-throughput

0.479

High

644730

CLH
Clathrin heavy chain

1

1

High-throughput

0.479

High

736074

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

4

High-throughput

0.479

High

736079

SLA2
Protein SLA2

1

20

High-throughput

0.479

High

736098

DHH1
ATP-dependent RNA helicase DHH1

1

8

High-throughput

0.479

High

736112

GTS1
Protein GTS1

1

1

High-throughput

0.479

High

736153

DBP10
ATP-dependent RNA helicase DBP10

1

8

High-throughput

0.479

High

736072

RAD23
UV excision repair protein RAD23

1

5

High-throughput

0.470

High

736131

IMA1
Importin subunit alpha

1

6

Small-scale

0.470

High

517948

SSBP1
Single-stranded nucleic acid-binding protein

1

7

High-throughput

0.457

High

651910

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

2

High-throughput

0.457

High

736075

PRP40
Pre-mRNA-processing protein PRP40

1

7

High-throughput

0.457

High

736117

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

3

High-throughput

0.457

High

367717

ENO1
Enolase 1

1

2

High-throughput

0.457

High

386624

TBB
Tubulin beta chain

1

3

High-throughput

0.457

High

405054

LEU3
3-isopropylmalate dehydrogenase

1

1

High-throughput

0.457

High

439286

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.457

High

456360

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

1

High-throughput

0.457

High

486086

TBA1
Tubulin alpha-1 chain

1

7

High-throughput

0.457

High

486430

TBA3
Tubulin alpha-3 chain

1

7

High-throughput

0.457

High

555034

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.457

High

590569

HSP26
Heat shock protein 26

1

1

High-throughput

0.457

High

661595

MPCP
Mitochondrial phosphate carrier protein

1

3

High-throughput

0.457

High

736084

EF1G2
Elongation factor 1-gamma 2

1

2

High-throughput

0.457

High

736100

MET10
Sulfite reductase [NADPH] flavoprotein component

1

1

High-throughput

0.457

High

736114

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.457

High

736150

HSP42
Heat shock protein 42

1

1

High-throughput

0.457

High

510294

HSP77
Import motor subunit, mitochondrial

1

7

High-throughput

0.445

High

736103

HSP7E
Heat shock protein SSC3, mitochondrial

1

7

High-throughput

0.445

High

736105

SSB2
Ribosome-associated molecular chaperone SSB2

1

5

High-throughput

0.445

High

381944

H4
Histone H4

1

4

High-throughput

0.437

High

401927

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

High-throughput

0.437

High

434919

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.437

High

558636

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.437

High

647043

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.437

High

670458

SIS1
Protein SIS1

1

6

High-throughput

0.437

High

706480

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

709621

BMH1
Protein BMH1

1

4

High-throughput

0.437

High

734882

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.437

High

736092

ECM29
Proteasome component ECM29

1

6

High-throughput

0.437

High

736093

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.437

High

736099

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

736101

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.437

High

736111

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.437

High

736127

H3
Histone H3

1

6

High-throughput

0.437

High

736135

POB3
FACT complex subunit POB3

1

1

High-throughput

0.437

High

736136

ENT2
Epsin-2

1

5

High-throughput

0.437

High

736142

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

736146

MCA1
Metacaspase-1

1

1

High-throughput

0.437

High

736156

ENT1
Epsin-1

1

1

High-throughput

0.437

High

736130

ADA2
SAGA complex subunit ADA2

1

9

High-throughput

0.407

High

736144

PUF3
mRNA-binding protein PUF3

2

0

Small-scale

0.318

High

550754

INO1
Inositol-3-phosphate synthase

1

0

High-throughput

0.282

High

736085

PGM2
Phosphoglucomutase 2

1

0

High-throughput

0.282

High

368330

TRPG
Multifunctional tryptophan biosynthesis protein [Includes: Anthranilate synthase component 2

1

0

High-throughput

0.279

Low

575409

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.279

Low

649212

SAN1
Protein SAN1

1

0

High-throughput

0.279

Low

736073

KA122
Importin beta-like protein KAP122

1

0

High-throughput

0.279

Low

736087

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.279

Low

736095

FET3
Iron transport multicopper oxidase FET3

1

0

High-throughput

0.279

Low

736121

SGF73
SAGA complex subunit SGF73

1

0

High-throughput

0.279

Low

736115

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.261

Low

736140

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.261

Low

368625

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.261

Low

425117

OTC
Ornithine carbamoyltransferase

1

0

High-throughput

0.261

Low

585539

BGL2
Glucan 1,3-beta-glucosidase

1

0

High-throughput

0.261

Low

673480

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

0

High-throughput

0.261

Low

701498

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

0

High-throughput

0.261

Low

736106

MPM1
Mitochondrial peculiar membrane protein 1

1

0

High-throughput

0.261

Low

736071

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

Small-scale

0.249

Low

736082

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

736104

YEY6
MYG1 protein YER156C

1

0

Small-scale

0.249

Low

736138

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

736145

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

Small-scale

0.249

Low

736094

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025