Interactor 1: RPB2 (P08518)
DNA-directed RNA polymerase II subunit RPB2 (RNA polymerase II subunit 2) (EC 2.7.7.6) (B150) (DNA-directed RNA polymerase II 140 kDa polypeptide)
Gene: RPB2

Interactor 2: RPAB2 (P20435)
DNA-directed RNA polymerases I, II, and III subunit RPABC2 (RNA polymerases I, II, and III subunit ABC2) (ABC23) (DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide)
Gene: RPO26

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.965

The method score is based on:

Property Details
Experiments 10784442, 18467557, 37968396, 8887628, 16554755, 16429126, 36411341
Identification Methods x-ray crystallography, protein complementation assay, affinity chromatography technology, dihydrofolate reductase reconstruction, tandem affinity purification
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb2_7~RNA_pol_Rpb6
Common GO terms GO:0001055 - RNA polymerase II activity
GO:0001172 - RNA-templated transcription
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005665 - RNA polymerase II, core complex
and 3 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 1224
Sc

1 155
+ Hs
+ Sp
+ Hs
+ Sc
+ Hs
+ Pf
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024